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  • Stress-Tolerant Cells Drive Tumor Initiation in Pancreatic Cancer

    Researchers at University of California San Diego School of Medicine have discovered a molecular pathway critical to the initiation of pancreatic tumors. The mechanism could also contribute to the disease’s high resistance to chemotherapy and its propensity for metastasis.

  • Researchers Use AI to Triage Patients with Chest Pain

    AI may help improve care for patients who show up at the hospital with acute chest pain, according to a study published in Radiology.

    “To the best of our knowledge, our deep learning AI model is the first to utilize chest X-rays to identify individuals among acute chest pain patients who need immediate medical attention,” said the study’s lead author, Márton Kolossváry, MD, PhD, radiology research fellow at Massachusetts General Hospital (MGH) in Boston.

  • A new mechanism discovered behind osteoarthritis, may shed light on new therapies

    Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity. These findings enhance the understanding of mechanisms that lead to the deterioration of joints that causes osteoarthritis, according to the authors of a new study, published January 10th in Nature Communications.

  • Reducing elevated level of Aldosterone can cure High BP

    Doctors at Queen Mary University of London and Barts Hospital, and Cambridge University Hospital, have led research using a new type of CT scan to light up tiny nodules in a hormone gland and cure high blood pressure by their removal. The nodules are discovered in one-in-twenty people with high blood pressure.

  • Inflammatory trigger a new clue in Alzheimer’s

    Scientists from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) reported that an inflammatory trigger like one present during viral infections is elevated in Alzheimer’s disease and progressive supranuclear palsy, a rare brain disorder.

    “We have identified a new trigger of brain inflammation in these disorders,” said Elizabeth Ochoa, PhD, study author from UT Health San Antonio. The finding, published in Science Advances, is novel for this reason, she said.

  • Protein complexes assemble at the cell membrane in a polarised manner

    Researchers at the Department of Microbiology and Cell Biology (MCB), Indian Institute of Science (IISc), Bengaluru, have deciphered how specific essential protein complexes are distributed across two different regions in the cell membrane. The findings also help us understand how they play a crucial role in coordinating chromosome segregation with cleavage furrow formation during anaphase. An article has been published on the IISc website, making this announcement.

  • How individual bacteria reacts when exposed to different antibiotics

    Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments. A group of researchers at Uppsala University have studied how individual bacteria react when exposed to different antibiotics. The result underlines the importance of adhering strictly to antibiotic prescriptions.

    Fighting bacterial diseases is a perpetual arms race between medical scientists developing new therapeutics and the pathogenic bacteria continuously changing their genetic makeup to survive the drugs.

  • Exercise restrains Insulin Production, breakthrough research

    When a fruit fly starts walking or flying, its insulin-producing cells are immediately inhibited. This could be one explanation for why exercise promotes health.

    Insulin is an essential hormone for humans and many other living creatures. Its best-known task is to regulate sugar metabolism. How it does this job is well understood. Much less is known about how the activity of insulin-producing cells and consequently the secretion of insulin is controlled.

  • Enzyme that protects against viruses could Fuel Cancer Evolution

    A three-dimensional image of a cancer cell's nucleus obtained by Dr. Faltas and his team shows the APOBEC3G protein (green) inside the nucleus (blue).

    An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine. The finding suggests that the enzyme may be a potential target for future cancer treatments.

  • iNCOVACC is now available on CoWin

    Bharat Biotech International Limited (BB1L), a global leader in vaccine innovation and developer of vaccines for infectious diseases, today announced that iNCOVACC* (BBV154), is scheduled to be introduced in the country' as a booster dose shortly. Earlier this month, Bharat Biotech received approval from the Central Drugs Standard Control Organization (CDSCO) for the use of heterologous booster doses of iNCOVACC*.

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