Research News

Novartis announced new data from PSMAddition demonstrating improved prostate-specific antigen (PSA) responses with Pluvicto® (lutetium (177Lu) vipivotide tetraxetan) combined with standard of care (SoC) in PSMA-positive metastatic hormone sensitive prostate cancer (mHSPC). Data were presented as a rapid oral presentation at the American Urological Association Annual Meeting 2026.

Researchers have uncovered a surprising new mechanism behind memory loss in Alzheimer’s disease, identifying dopamine deficiency as a major contributor to cognitive decline. The discovery could open the door to new treatment approaches aimed at restoring memory in patients suffering from the disease.

The study was led by scientists at Tohoku University in collaboration with researchers from the University of California, Irvine. Their findings were published in the journal Nature Neuroscience on April 23, 2026.

A major breakthrough in diabetes research could one day free patients with type 1 diabetes from lifelong insulin injections. Researchers from Université de Genève and Geneva University Hospitals have developed an innovative protective hydrogel capable of supporting insulin-producing cells after transplantation, successfully restoring blood sugar control in diabetic mice.

The World Health Organization has officially declared the ongoing Ebola outbreak in the Democratic Republic of the Congo and Uganda a “Public Health Emergency of International Concern” (PHEIC), raising global alarm over the rapid spread of the deadly virus across Central Africa.

People who have survived a heart attack could be at a greater risk of experiencing faster declines in memory and thinking abilities as they age, according to a new study published in the journal Stroke.

Researchers found that adults with a prior heart attack had a significantly higher likelihood of developing cognitive impairment over time compared to individuals without a history of heart attack. The findings highlight a growing connection between heart health and brain health, especially among older adults.

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent osteoblasts in inactive bone surfaces return to an active state. Using spatial transcriptomics, single-cell analysis, and functional experiments, researchers identified TGF-β signaling as a regulator of osteoblast activation. In a bone-loss mouse model, dual inhibition of TGF-β and sclerostin increased bone mass more effectively than sclerostin inhibition alone, highlighting a promising combination strategy.

A surprising breakthrough in anti-aging research raises hopes of delaying muscle aging and weakness by harnessing the potential of a garlic-derived compound, S-1-propenyl-L-cysteine (S1PC). Researchers identify a key role for S1PC in orchestrating a key inter-organ communication between fat tissue and the hypothalamus in the brain, thus supporting muscle function in aged mice. Elements of this signaling mechanism were also observed in humans, highlighting the potential of S1PC-based anti-aging interventions.

Short QT syndrome is a genetic disease that leads to sudden cardiac death at a young age. Mutations in the SLC4A3 gene, which regulates bicarbonate-chloride exchange, were recently described as a potential cause. An international research team including a group from Ruhr University Bochum, Germany, investigated this possibility. The researchers discovered how different variants of the gene affect heart muscle cells: Specifically, the pH level increased and the flow of ion channels was altered. This insight could aid in providing better personal care for persons affected by the disease.