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Research News

  • Nasal spray flu vaccine candidate based on UW–Madison technology shows promise when administered alongside high dose annual shot

    A unique influenza vaccine candidate that’s inhaled and based on technology developed by University of Wisconsin–Madison researchers is safe and could bolster protection against seasonal and pandemic influenza for people vulnerable to severe disease when they receive it in addition to the annual flu shot.

  • Sleep resets neurons for new memories the next day
    Learning or experiencing new things activates neurons in the hippocampus, a region of the brain vital for memory. Later, while we sleep, those same neurons repeat the same pattern of activity, which is how the brain consolidates those memories that are then stored in a large area called the cortex.
  • Imfinzi granted Priority Review and Breakthrough Therapy Designation for patients with limited-stage small cell lung cancer in the US
    Food and Drug Administration grants Priority Review to applications for medicines that, if approved, would offer significant improvements over available options by demonstrating safety or efficacy improvements, preventing serious conditions or enhancing patient compliance.
  • University of Houston Researchers Create New Treatment and Vaccine for Flu and Various Coronaviruses

    A team of researchers, led by the University of Houston, has discovered two new ways of preventing and treating respiratory viruses. In back-to-back papers in Nature Communications, the team from the lab of Navin Varadarajan, M.D. Anderson Professor of William A.

  • Could This New Drug Turn Back the Clock on Multiple Sclerosis?
    Multiple sclerosis degrades the protective insulation around nerve cells, leaving their axons, which carry electrical impulses, exposed like bare wires. This can cause devastating problems with movement, balance and vision; and without treatment, it can lead to paralysis, loss of independence and a shortened lifespan.
  • Discovery of a new population of macrophages promoting lung repair after viral infections
    Respiratory viruses, typically causing mild illness, can have more serious consequences, as shown during the Covid-19 pandemic, including severe cases requiring hospitalization and the chronic sequelae of long Covid.
  • High blood pressure associated with environmental contamination by tellurium
    The likelihood of developing high blood pressure increases with higher levels of tellurium, a contaminant transferred from mining and manufacturing activities to foods. Improved monitoring of tellurium levels in specific foods could help decrease high blood pressure in the general population. The results of a study examining the relationship between tellurium exposure and hypertension were published in the journal Environment International.
  • AI Opens Door to Safe, Effective New Antibiotics to Combat Resistant Bacteria
    In a hopeful sign for safe, effective antibiotics for humans, researchers at The University of Texas at Austin have leveraged aritificial intelligence to develop a new drug that already is showing promise in animal trials. Publishing their results today in Nature Biomedical Engineering, the scientists describe using a large language model an AI tool like the one that powers ChatGPT to engineer a version of a bacteria-killing drug that was previously toxic in humans, so that it would be safe to use.
  • The virus that causes COVID-19 is widespread in wildlife : Scientists find

    SARS-CoV-2, the virus responsible for COVID-19, is widespread among wildlife species, according to Virginia Tech research published today in Nature Communications. The virus was detected in six common backyard species and antibodies indicating prior exposure to the virus were found in five species with rates of exposure ranging from 40 to 60 percent depending on the species.

  • Improving the Design of mRNA-loaded Nanocarriers for Targeted Therapies

    Substituting amines with phosphonium-based cations could greatly improve the performance of mRNA-loaded polymeric micelles, report scientists from Tokyo Tech. By adopting this innovative strategy, they managed to enhance the stability and mRNA-delivery capabilities of micelle nanocarriers into tumor tissue in vivo. Their results hint at the importance of exploring other cations besides amines in mRNA drug delivery and could pave the way to effective treatment for challenging diseases.

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