Research News

Scientists found molecules that convert White fat to Brown / Good Fat

  • Posted on: 10 December 2014
  • By: PharmaTutor News

Harvard Stem Cell Institute (HSCI) researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of obesity, though that shift, of course, would not provide all of the many benefits of exercise.

3D vaccines injection could fight cancer and HIV

  • Posted on: 10 December 2014
  • By: PharmaTutor News

One of the reasons cancer is so deadly is that it can evade attack from the body's immune system, which allows tumors to flourish and spread. Scientists can try to induce the immune system, known as immunotherapy, to go into attack mode to fight cancer and to build long lasting immune resistance to cancer cells. Now, researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University and Harvard's School of Engineering and Applied Sciences (SEAS) show a non-surgical injection of programmable biomaterial that spontaneously assembles in vivo into a 3D structure could fight and even help prevent cancer and also infectious disease such as HIV. Their findings are reported in Nature Biotechnology.

Plastic can be degraded by gut bacteria from worms

  • Posted on: 4 December 2014
  • By: PharmaTutor News

Plastic is well-known for sticking around in the environment for years without breaking down, contributing significantly to litter and landfills. But scientists have now discovered that bacteria from the guts of a worm known to munch on food packaging can degrade polyethylene, the most common plastic. Reported in the ACS journal Environmental Science & Technology, the finding could lead to new ways to help get rid of the otherwise persistent waste, the scientists say.

GSK's Ebola Vaccine appears safe and shown encouraging immune response

  • Posted on: 1 December 2014
  • By: PharmaTutor News

An experimental vaccine to prevent Ebola virus disease was well-tolerated and produced immune system responses in all 20 healthy adults who received it in a phase 1 clinical trial conducted by researchers from the National Institutes of Health. The candidate vaccine, which was co-developed by the NIH’s National Institute of Allergy and Infectious Diseases (NIAID) and GlaxoSmithKline (GSK), was tested at the NIH Clinical Center in Bethesda, Maryland. The interim results are reported online in advance of print in the New England Journal of Medicine.

Leg Attacks can be Fatal if they Remain Undiagnosed

  • Posted on: 17 November 2014
  • By: PharmaTutor News

(17th November, 2014; Business Wire India); We are all aware of the dangers of a heart attack, few are aware of an equally dangerous condition called “Leg Attacks”. Quite similar to heart attacks, leg attacks occur when there are blockages in the blood vessels of the leg. This condition is exacerbated in Diabetics, those aged above 50 and smokers who are at a higher risk of developing blockages or peripheral vascular diseases. Leg attack is one of the extreme conditions arising from blockages in the vessels of the limbs which can lead to non healing ulcer even limb amputation. Most doctors agree that despite the severity of leg attacks, most cases remain undiagnosed till the last stage due to a lack of awareness of the disease and its symptoms.

Psoriasis Drug of Amgen and AstraZeneca conquered blockbuster Stelara

  • Posted on: 12 November 2014
  • By: PharmaTutor News

(12th November, 2014); Brodalumab, a novel psoriasis drug from colloboration of Amgen and Astrazeneca shown superior results in compare to Stelara® (ustekinumab) in head to head trials. The trial conducated on moderate-to-severe plaque psoriasis which met its primary endpoints when compared with both Stelara and placebo at week 12. Brodalumab was shown to be superior to Stelara on the primary endpoint of achieving total clearance of skin disease, as measured by the Psoriasis Area Severity Index (PASI 100).

New drug found to improve liver health in common liver disease

  • Posted on: 11 November 2014
  • By: PharmaTutor News

An experimental drug aimed at treating a common liver disease showed promising results and potential problems in a multicenter clinical trial funded by the National Institutes of Health. The FLINT study found that people with nonalcoholic steatohepatitis (NASH) who took obeticholic acid (OCA) had improved liver health during that period, including decreased inflammation and fat in the liver and decreased body weight versus people receiving a placebo. OCA was also associated with increases in itching and total cholesterol.

PETN, organic compound found which reduced BP in female offspring of hypertensive rats

  • Posted on: 11 November 2014
  • By: PharmaTutor News

(11th November, 2014); The explosive organic compound pentaerythritol tetranitrate (PETN) might one day allow pregnant women to protect their daughters from developing high blood pressure (BP) before they’re born, according to an animal study published in the American Heart Association’s journal Hypertension.


Researchers capture the emergence of multicellular life in real-time experiments

  • Posted on: 10 November 2014
  • By: PharmaTutor News

(10th November, 2014); All multicellular creatures are descended from single-celled organisms. The leap from unicellularity to multicellularity is possible only if the originally independent cells collaborate. So-called cheating cells that exploit the cooperation of others are considered a major obstacle. Scientists at the Max Planck Institute for Evolutionary Biology in Plön, Germany, together with researchers from New Zealand and the USA, have observed in real time the evolution of simple self-reproducing groups of cells from previously individual cells.

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