Research News

Zinc, folic acid supplement does not improve male fertility, NIH study suggests

  • Posted on: 9 January 2020
  • By: Shalini.Sharma

Dietary supplements containing zinc and folic acid — marketed as a treatment for male infertility — do not appear to improve pregnancy rates, sperm counts or sperm function, according to a study conducted by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health. The study appears in the Journal of the American Medical Association.

Possible dementia vaccine closer after mice studies

  • Posted on: 31 December 2019
  • By: Shalini.Sharma

A preventive treatment for dementia may proceed to clinical trials after successful animal testing.

The US-led research is looking to develop effective immunotherapy via a new vaccine to remove 'brain plaque' and tau protein aggregates linked to Alzheimer's disease.

Recent success in bigenic mice models supports progression to human trials in years to come, the researchers say.

CRI scientists discover metabolic feature that allows melanoma cells to spread

  • Posted on: 19 December 2019
  • By: PharmaTutor News

Researchers at Children's Medical Center Research Institute at UT Southwestern (CRI) have uncovered why certain melanoma cells are more likely to spread through the body. The discovery opens up a potential new avenue of treatment and could be used to help reduce the proportion of patients who progress from stage 3 melanoma to more-deadly stage 4 cancer.

AI can detect risk of diabetes on basis of lipid profile

  • Posted on: 18 December 2019
  • By: PharmaTutor News

Using lipidomics, a technique that measures the composition of blood lipids at a molecular level, and machine learning, researchers at Lund University in Sweden have identified a blood lipid profile that improves the possibility to assess, several years in advance, the risk of developing type 2 diabetes. The blood lipid profile can also be linked to a certain diet and degree of physical activity.

Blood contains hundreds of different lipid molecules that are divided into different classes, such as cholesterol and triglycerides.

Researchers identify drug targets for the dreaded Nipah virus

  • Posted on: 17 December 2019
  • By: PharmaTutor News

Taking the fight against the dreaded Nipha disease to a new level, researchers at Pune-based Indian Institute of Science Education and Research (IISER) have developed drug targets for the virus that causes the disease, using the molecular modeling approach.

Nipah virus outbreaks have very high mortality rates. They are over 70 per cent in Southeast Asia. The virus spreads via bodily secretions of bats, pigs and infected individuals. It was first detected in human population in 1998 in Malaysia, It made its way into Indian subcontinent with outbreaks in Bangladesh and India a few years later.

Herbal extract may help better uptake of Vitamin B12

  • Posted on: 16 December 2019
  • By: PharmaTutor News

A common concern with oral vitamin B12 therapy is absorption especially in people suffering from anemia and gastrointestinal diseases. Researchers at the Council of Scientific and Industrial Research-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP) have identified a plant extract that has shown potential in enhancing absorption of vitamin B12 through in vitro and in vivo bioassays.