Researchers have developed an innovative oxygen-boosted microneedle patch that significantly improves drug delivery and photodynamic therapy (PDT) for psoriasis, a chronic inflammatory skin disease that affects millions worldwide.
The study, published in Acta Pharmaceutica Sinica B, describes a dual-section microneedle (MN) patch designed to overcome two major challenges in psoriasis treatment: poor drug penetration through thickened skin and reduced efficacy of PDT caused by low oxygen levels in inflamed lesions.