The Department of Biotechnology (DBT), Ministry of Science & Technology, Government of India (GoI) has taken myriads of initiatives to increase investments in research & development (R&D) and manufacturing of COVID-19 Vaccines.
The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation.
However, much remains to be learned about various mutations that lead to a “loss of function” in the protein and others that cause a putative malignant “gain of function,” acceleration of cancerous growth and spread (metastasis), for example.
Vaccinations against human papillomavirus (HPV), a major cause of throat and back of mouth cancers, are expected to yield significant reductions in the rates of these cancers in the U.S., but will not do so until after 2045, according to a new modeling study from researchers at the Johns Hopkins Bloomberg School of Public Health.
The International Vaccine Institute announced the first participant received Bharat Biotech International Ltd’s (BBIL) Chikungunya vaccine candidate (BBV87) in a Phase II/III clinical trial in Costa Rica, marking the start of a multi-country study led by IVI in partnership with BBIL and funded by the Coalition for Epidemic Preparedness Innovations (CEPI) with support from the Ind-CEPI mission of the Department of Biotechnology, India.
In a study published in Molecular Psychiatry, the team show that changes in the extracellular matrix of the brain – scaffolding around nerve cells – lead to loss of memory with ageing, but that it is possible to reverse these using genetic treatments.
Cutting 20% of sugar from packaged foods and 40% from beverages could prevent 2.48 million cardiovascular disease events (such as strokes, heart attacks, cardiac arrests), 490,000 cardiovascular deaths, and 750,000 diabetes cases in the U.S. over the lifetime of the adult population, reports a study published in Circulation.
Organ transplantation involves the transplantation of organs from donors as a means to treat disease or injury, but there is a shortage of organs available for donation compared to the demand for organ transplantation. Research involving the transplantation of animal organs (xenotransplantation) is ongoing, considering its potential to overcome these challenges.
The largest analysis aimed at more accurately predicting the risk of sudden cardiac death after myocardial infarction is presented in late breaking results from the PROFID consortium at ESC Congress 2021.
Department of Biotechnology, Ministry of Science and Technology, Government of India in collaboration with BRICS countries is implementing SARS-CoV-2 NGS-BRICS consortium and multi centric programme to study the impact of severe COVID-19 conditions on TB patients.
DELFI blood test identifies lung cancer using artificial intelligence to detect unique patterns in the fragmentation of DNA shed from cancer cells compared to normal profiles. Credit: Carolyn Hruban
A novel artificial intelligence blood testing technology developed by researchers at the Johns Hopkins Kimmel Cancer Center was found to detect over 90% of lung cancers in samples from nearly 800 individuals with and without cancer.