Singh Deep Hussan*, Roychowdhury Santanu
Sri Sai college of pharmacy, badhani,
Mucoadhesion is the prevalent interest in the design of drug delivery systems. Mucoadhesion can be defined as the state in which two materials, at least one of which is biological (mucosa) in nature, are held together for a prolonged time period by means of interfacial forces. This mucoadhesive system offers many advantages as it allows for reduction in daily administrations and daily drug dosage and is suitable for the treatment of irritation, pain, and discomfort associated with gingivitis, sore throats, laryngopharyngitis, cold, and periodontal surgery. Moreover, it adheres well to the gum and is very simple to apply, which means that patient compliance is improved. Mucoadhesive drug delivery system are designed to enable prolonged residence time of the dosage form at the site of application or absorption and facilitate an intimate contact of the dosage form with the underline absorption surface. The present review describes mucoadhesion, mucoadhesive polymers and their classification, stages, mechanism and theories of mucoadhesion and factors affecting them along with its evaluation. However, the research on mucoadhesives, is still in its early stage and further advances need to be made for the successful translation of the concept into practical application in controlled drug delivery.
The PGIMER owes its inception to the vision of late Sardar Partap Singh Kairon, the then Chief Minister of Punjab and the distinguished medical educationists of the then combined state of Punjab, supported by the first Prime Minister of India Pt.
IOL Chemicals Pharmaceuticals Limited, Leading manufacturers of Ind'l Chemicals & Pharma APIs. Formidable presence in country for its chemicals - Acetic Anhydride, Ethyl Acetate, MCA. One of the largest producers of Pharma API-Ibuprofen in the world. Annual turnover of approx.
Post: Instrument Technician /SR. Technician
The University Institute of Pharmaceutical Sciences of the Panjab University is a premier institution of Pharmaceutical Education and Research in the country.
Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services.
The University Institute of Pharmaceutical Sciences of the Panjab University is a premier institution of Pharmaceutical Education and Research in the country. The institute has covered a long and glorious journey of 76 years starting from Lahore in 1944 and finally settling to the present campus in Chandigarh at the foothills of Himachal.
Applications are invited from the eligible candidates, in the prescribed proforma, for filling up the following Group ‘A’ Medical Faculty posts, purely on contract basis, in Government Medical College & Hospital, Sector-32, Chandigarh.
Assistant Professor, CT Institute of Pharmaceutical Sciences,
Phytosomes are little cell like structure which are also termed herbosomes which are formed by complexation of the polyphenolic phytoconstituents in molar ratio with phosphatidylcholine. Bioavailability of flavonoid containing phytomedicines, is reported to be low and erratic due to limited absorption, elevated presystemic metabolism and rapid elimination. But their phytosomal formulations show improved absorption, enhanced delivery and increased bioavailability of phytochemicals than the conventional herbal extracts containing dosage forms. Phytosome technology has been effectively used to enhance the bioavailability of many popular herbal extracts e.g. milk thistle, grape seed, green tea, hawthorn, etc. The improved pharmacokinetic and pharmacological properties of phytosomes make them suitable for the treatment of serious degenerative disorders. This article reviews the recent trends and applications of various herbal extract phytosomes as a tool of drug delivery system and as an emerging technology for increasing bioavailabity of phytoconstituents.