Skip to main content

Guntur

 

Clinical courses

  • Walk in Interview for the post of Professors, Associate Professors, Asst. Professors & Lab Technician in NARASARAOPETA Institute of Pharmceutical Sciences

    Narasaraopeta institute of pharmaceutical sciences is a premier educational institute promoted by Gaythri educational development society (GEDS), under the leadership of Sri. Mittapalli Venkata Koteswara rao. The college is situated a little away from narasarapeta town (2Km), towards Kottappakonda. (Historic temple of Trikoteswara swamy, Kottappakonda.)

    Post: Professors, Associate Professors, Asst. Professors & Lab Technician

  • Job as Asst. Professors at K C Reddy Institute of Pharmaceutical Sciences

    K.C.REDDY college was established in the year 2007, and sponsored by NRI'S K.C.REDDY COLLEGE, the parent educational organisation of is a Balaji Educational Society, established in the year 2007 to contribute and serve the educational field by establishing schools, colleges and technological institutions to impart quality oriented, merit-targeted education. K.C.REDDY COLLEGE was established in August 2007 with the approval of AICTE, New Delhi and is affiliated to ANU,Guntur Andhra Pradesh

    Post: Asst. Professors-01

  • Walk in interview for various departments of HETERO

    HETERO, research based approved USFDA, TGA, EU, PMDA, KFDA and WHO global pharmaceutical company established in 1993, focused on development, manufacturing and marketing of Active Pharmaceutical Ingredients (APIs), Intermediate Chemicals & Finished Dosages.

    We are looking for freshers for our units located at Hyderabad.

  • EVLUATION OF EFFECTS OF COMMIPHORA WIGHTII IN DEHYDROEPIANDROSTERONE (DHEA) INDUCED POLYCYSTIC OVARY SYNDROME (PCOS) IN RATS
  • A.M. Reddy Memorial College of Pharmacy requires Faculty position | Specialization of Pharmaceutics, Analysis, Pharmaceutical Chemistry, Pharmacology, Pharmacognosy & Pharm.D

    A.M. Reddy Memorial College of Pharmacy was founded in 2003 by NRIs Sri. Atluri Srinivasa Reddy and Mrs. Atluri Santhi under Atluri Mastan Reddy Educational Society, which is situated at Petlurivaripalem, Narasaraopet. The college is housed independently pollution free, picturesque lush green environment with a well-equipped with the state of art facilities. It is approved by AICTE(All India Council for Technical Education), New Delhi and PCI(Pharmacy Council of India), New Delhi. The college has been ever-driven by the greater aspirations to provide the finest quality of Pharmacy Education, richly implanted in its brilliant infrastructure and ultra modern resources to ultimately mould every student with academic excellence.

    Post: Professors/ Associate Professors/ Assistant Professors

  • Walk in interview on Pharmacists in ECHS Polyclinics in Telangana & Andhra pradesh

    ECHS invites applications to engage following Staff on contractual basis in ECHS Polyclinics in Telangana & Andhra pradesh for a Period of one year, renewable for additional period:

    Post: Pharmacist

  • FORMULATION DEVELOPMENT AND IN VITRO CHARACTERIZATION OF SUSTAINED RELEASE PELLETS OF VENLAFAXINE HCl

    About Author:
    Anitha Nidadavolu
    Department of Industrial Pharmacy
    Chalapathi Institute of Pharmceutical Sciences
    Chalapathi Nagar, Lam, Guntur-522034,
    Andhra Pradesh, India.
    anitha058@gmail.com

    { DOWNLOAD AS PDF }

    Abstract:
    In the present study, an attempt was made to develop and characterize once daily sustained release pellets of highly water soluble drug Venlafaxine Hydrochloride, which is an antidepressant of serotonin-nor epinephrine reuptake inhibitor (SNRI). Compatibility studies by FTIR spectroscopy observed Venlafaxine HCl was compatible with all the excipients used. These pellets were prepared in three stages. In drug loading stage (powder layering technique with pan coater), drug was loaded on non-pareil sugar spheres by using Mannitol, Microcrystalline powder (MCCP) as diluents and PVP K30 as binder. The concentration of Venlafaxine HCl was kept constant. Four preliminary batches of drug loaded pellets prepared by varying concentrations of disintegrant Crospovidone INF-10 (D1- D4) i.e. 1.5%, 3%, 4.5%, 6%. Optimized formulation was selected based on percentage yield, drug content (assay) and found D3- 4.5% as best. In barrier coating stage(wurster process with fluidized bed coater) drug loaded pellets of D3 were coated by different concentrations of film former HPMC E3 (B1- B3) i.e.4%, 6%, 8%. Among them, B2- 6% found as best. In SR coating stage (wurster process with fluidized bed coater) barrier pellets of B2 were coated by varying concentrations of release rate retarding polymer Ethyl cellulose EC 7 cps (S1- S4) i.e. 2%, 5%, 6%, 8%. These EC (S1- S4) formulations were characterized fordrug content (assay), particle size distribution, friability,flow properties, surface morphology (SEM) and dissolution profile.In vitro dissolution studies were carried out by USP dissolution apparatus Type-II and compared with innovator Effexor XR®. Among all formulations S4(8%) was best, followed first order kinetics and found to release the drug over a sustained period of time up to 24 hrs. The release exponent (n values) for all found in the range of n > 1, indicated that the drug transport mechanism by super case-II transport. The optimized S4 formulation was found as pharmaceutically equivalent to innovator due to similarity (f2 =77.77) in drug release profile. As per ICH guidelines, accelerated stability studies conducted and there was no significant difference in physicochemical parameters (p < 0.05), indicated that the optimized S4 formulation was stable.

  • DETERMINATION OF PURITY AND RELATIVE MOLECULAR WEIGHT OF PURIFIED HUMAN IgG

    About Authors:
    1M Prasad Naidu, 2Dr Madhu Sudan Reddy, 3T Madhu Chaithanya, 4N Mallikarjun Rao

    1(Medical Biochemistry) NMCH, Nellore, AP, India.
    2(MD Pharmacolgy) NMCH, Nellore, AP, India.
    3(Medical Pharmacology) MIMS, Vijayanagaram, AP, India.
    4(MSc Botany). Acharya Nagarjuna University, Guntur, AP, India.
    *www.prasadnaidu.com@gmail.com

    Sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE)
    An important technique for the separation of proteins is based on the migration of charged proteins in an electric field, a process called electrophoresis. These procedures are not generally used to purify proteins in large amounts, because simpler alternatives are usually available and electrophoretic methods often adversely affect the structure and thus the function of proteins. Electrophoresis is, however, especially useful as an analytical method. Its advantage is that proteins can be visualized as well as separated, permitting a researcher to estimate quickly the number of different proteins in a mixture or the degree of purity of a particular protein preparation. Also, electrophoresis allows determination of crucial properties of a protein such as its isoelectric point and approximate molecular weight. The polyacrylamide gel acts as a molecular sieve, slowing the migration of proteins approximately in proportion to their charge-to-mass ratio. Migration may also be affected by protein shape. In electrophoresis, the force moving the macromolecule is the electrical potential, E. The electrophoretic mobility of the molecule, µ, is the ratio of the velocity of the particle molecule, V, to the electrical potential. Electrophoretic mobility is also equal to the net charge of the molecule, Z, divided by the frictional coefficient, f, which reflects in part a protein’s shape.

  • CONSIDERATIONS FOR BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION BY USING LC-MS/MS-A REVIEW

    ABOUT AUTHOR:
    Bhimavarapu Ramya Reddy
    Department of Pharmaceutical Analysis,
    A.M Reddy Memorial College of Pharmacy, Narasaraopet,
    Guntur, Andhra Pradesh, India.
    ramyareddy.bh@gmail.com

  • METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF AMLODIPINE AND INDAPAMIDE BY DIFFERENT SPECTROPHOTOMETRIC AND RP-HPLC METHODS IN BULK DRUG AND PHARMACEUTICAL FORMULATION

    ABOUT AUTHORS:
    Madhuri tadiparthi
    Chalapathi institute of pharmaceutical sciences,
    guntur, a.p, india.
    tadiparthimadhuri@gmail.com

    ABSTRACT:
    Amlodipine
     (as besylate, mesylate or maleate) is a long-acting calcium channel blocker (dihydropyridine (DHP) class) used as an anti-hypertensive and in the treatment of angina. Indapamide is a thiazide diuretic used in the treatment of hypertension, as well as decompensated cardiac failure. Six new, simple, accurate and precise methods have been developed and validated according to ICH guidelines for the simultaneous estimation of Amlodipine and Indapamide in their combined dosage form (four UV-Spectrophotometric, one colorimetric and one RP-HPLC methods).
    First method is based on simultaneous estimation using two wavelengths, 365 nm (λmaxof AMLO) and 279 nm (λmaxof INDA) by simultaneous equation method. The second method involves the use of first order derivative technique, here 293 nm, the zero crossing point of AMLO, 279 nm, the zero crossing point of INDA were used for the estimation. The third method is based on Q-absorption Ratio method using two wavelengths 365 nm (λmaxof AMLO) and 312 nm (Isoabsorptive point). In the dual wavelength method two wave lengths 270 nm and 288 nm were selected as λ1 and λ2 for the estimation of AMLO, INDA shows the same absorbance at these wavelengths. Similarly, wavelengths 350 nm and 378 nm were selected as λ1 and λ2 for the estimation of INDA, AMLO shows the same absorbance at these wavelengths.Colorimetry:  The method is based on use of MBTH reagent for simultaneous estimation of AMLO and INDA using two wavelengths, 626 nm (λmaxof AMLO) and 600 nm (λmaxof INDA).

Subscribe to Guntur