Guntur

FOODS CONTAINING NITROSOAMINES CAUSES CARCINOGENESIS – AN INSIGHT REVIEW

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ABOUT AUTHORS
Sai Kushal Gunturu*, Tulasi Ram Nayak Menavath, Ramadoss Karthikeyan
Vignan Pharmacy College, Vadlamudi-522213, Guntur, Andhra Pradesh, India

ABSTRACT
Nitrosamines belongs to a family of potent carcinogenic substances that have been rigorously stidie dover the past decades due to its extreme carcinogenic nature to animals as well as humans. It is generally found as an industrial contaminant but can also the exposure to the substance maybe due to soil, water or food contamination. The carcinogenicity to humans is caused by the metabolised product of nitrosamines especially, N-nitroso compounds.

One of the most extensively studied compound of this fami.ly is N-Nitroso dimethylamine due to its potency in the formation of cancers. N-Nitroso dimethylamine induces cancers in the stomach due to its metabolism in the gut and the production of toxic metabolites. Frequently N-Nitroso dimethylamine exposure is via skin absorption and also via ingestion.

Under extensive researches in mice, in oral administration it is found to induce cancers of lung, kidney and stomach. It was proposed that the toxic nature of N-Nitroso dimethylamine is due to the highly – oxygen reactive species forming metabolite nature and also altering the activity of liver microsomal enzymes.

Job for Professor, Associate Professor, Assistant Professor at Bapatla College of Pharmacy

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Acharya Nagarjuna, the profounder of the Madhyamika Buddhism is one of the greatest philosophers India has ever produced. The Buddhists of China, Japan and Tibet river him to be the Second Buddha, who once again set in the motion the wheel of Dharma. He endowed with metaphysical profundity and logical acumen has reaffirmed the basic ideas of Buddhism, apart from providing reinterpretation, clarification and amplification of new concepts of Buddhism.

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Post : Faculty

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Please read below for positions available (with qualifications and salary details), point weightage/mode of selection and broad roles and responsibilities (subject to change). Please find the application to apply with instructions on what is required on the last 2 pages of this document. APPLICANTS WHO NOT FOLLOW INSTUCTIONS WILL BE DISQUALIFIED.

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