Rohtak

17 July 2013

Applications are invited for the post of Pharmacist (8 posts) in Pt. B. D. Sharma Postgraduate Institute of Medical Sciences

Applications are invited for the following temporar y posts but likely to be continued of Pt. B. D. Sharma Postgraduate Institute of Medical Sciences, Rohtak and Pt. B. D. Sharma University of Health Sciences, Rohtak on the prescribed form obtainable from the HDFC Bank, Model Town Branch, Rohtak on cash payment of Rs.300/-for General Category and Rs.100/ - for Reserved Categories candidates or by crossed Indian Postal Order in the name of the Controller of Finance, Pt. B. D.
30 April 2013

Walk in interview on B.Pharm, D.Pharm from Pharmacist in NRHM

Applications are invited on plain paper and walk in interview will be conducted for filling up the following post at Drug Warehouses to be setup at Districts Ambala, Karnal, Kaithal, Jind, Hisar, Rohtak, Gurgaon & Bhiwani under National Rural Health Mission, Haryana purely on contract basis and initially up to 31.03.2014 with details as mentioned below:
30 April 2013

Application are invited from Warehouse Manager in National Rural Health Mission | Walk in

Applications are invited on plain paper and walk in interview will be conducted for filling up the following post at Drug Warehouses to be setup at Districts Ambala, Karnal, Kaithal, Jind, Hisar, Rohtak, Gurgaon & Bhiwani under National Rural Health Mission, Haryana purely on contract basis and initially up to 31.03.2014 with details as mentioned below:
28 October 2012

EXTENDED RELEASE DRUG DELIVERY SYSTEM: A REVIEW

About Authors:
Mahek Goel*, Minakshi Marwaha
Shri Baba Mast Nath Institute of Pharmaceutical Sciences and Research, Asthal
Bohar, Rohtak-124001
*mahekgoel10@gmail.com

Abstract
Oral drug delivery system is the largest and the oldest segment of the total drug delivery market. As the drug which are presently available in the market suffered from the problem of resistance due to their irrational use as well as very few drugs are coming out of research and development, so there is need of the development of oral controlled drug delivery system (CDDS). Controlled release dosage forms are designed in such a way so that to maintain a constant level of drug for a specific period of time with minimum side effects. CDDS optimizes the biopharmaceutical, pharmacokinetic and pharmacodynamic properties in such a way that its dosing frequency is reduced to an extent that once daily administration is sufficient to maintain the desired therapeutic level of drug with reduction in side effects in shorter possible time to assure greater patient compliance. This review describes various advantages, disadvantages, types of modified release, desired characteristics, approaches and evaluation tests for controlled release dosage forms.
28 October 2012

REGISTRATION DOSSIER OF PHARMACEUTICALS

About Authors:
Apeksha Gupta
Maharshi Dayanand University,
Rohtak, India.
apekshagupta87@gmail.com

ABSTRACT
The word “Dossier” has its English meaning as - a collection or file of documents on the same subject, especially a file containing detailed information about a person or a topic. Any preparation for human use that is intended to modify or explore physiological systems or pathological states for the benefit of the recipient is called as “pharmaceutical product for human use”. Process of reviewing and assessing the dossier of a pharmaceutical product containing its detailed data (administrative, chemistry, pre-clinical and clinical) and the permission granted by the Regulatory Agencies of a country with a view to support its marketing / approval in a country is called as the “Marketing Approval or the “Registration” “Marketing Authorization” or the “Product Licensing”.
“Registration Dossier” of the pharmaceutical product is a document that contains all the technical data (administrative, quality, nonclinical and clinical) of a pharmaceutical product to be approved / registered / marketed in a country. It is more commonly called as the New Drug Application (NDA) in the USA or Marketing Authorization Application (MAA) in the European Union (EU) and other countries, or simply Registration Dossier. Basically, this consists of data proving that the drug has quality, efficacy and safety properties suitable for the intended use, additional administrative documents, samples of finished product or related substances and reagents necessary to perform analyzes of finished product. Therefore, they are the vehicle in a country through which drug sponsors formally propose that the Regulatory Agencies approve a new pharmaceutical for sale and marketing.

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23 October 2012

A REVIEW: PARENTERAL CONTROLLED DRUG DELIVERY SYSTEM

About Author:
Mahek Goel
Shri Baba Mastnath Institute of Pharmaceutical Science & Research
Asthal Bohar, Rohtak, Haryana (124001)
mahekgoel10@gmail.com

ABSTRACT
Parenteral drug delivery systems are the preparations that are given other than oral route. (Para-outside, enteric–intestine). Parenteral drug delivery systems are most preferred drug delivery systems as they meet many benefits over other dosage forms in many cases such as unconsciousness, nausea, in emergency clinical episodes. The Parenteral administration route is the most common and efficient for delivery of active drug substances with poor bio-availability and the drugs with a narrow therapeutic index. But parenteral route offers rapid onset of action with rapid declines of systemic drug level. For the sake of effective treatment it is often desirable to maintain systemic drug levels within the therapeutically effective concentration range for as long as treatment calls for. It requires frequent injection, which ultimately leads to patient discomfort. For this reason, drug delivery system which can reduce total number of injection throughout the effective treatment, improve patient compliance as well as pharmacoeconomic. These biodegradable injectable drug delivery system offer attractive opportunities for protein delivery and could possibly extend patent life of protein drugs.Parenteral drug delivery system seeks to optimize therapeutic index by providing immediate drug to the systemic pool in required quantity to treat– cardiac attacks, respiratory attacks. This article explores various prolonged release parenteral drug delivery system and their strategies of preparation, their potential benefits/drawbacks and in-vitro testing methods.
26 September 2012

Nanoparticles: An Overview

About Authors:
Mahek Goel
Shri Baba Mastnath Institute of Pharmaceutical Science & Research
Asthal Bohar, Rohtak, Haryana (124001)
mahekgoel10@gmail.com

Abstract:
Nanoparticles are the preparations having size in nanometers. Particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmacodynamic properties of various types of drug molecules. They have been used in vivo to protect the drug entity in the systemic circulation, restrict access of the drug to the chosen sites and to deliver the drug at a controlled and sustained rate to the site of action. Various polymers have been used in the formulation of nanoparticles for drug delivery research to increase therapeutic benefit, while minimizing side effects. Here, we review various aspects of nanoparticle formulation, characterization, effect of their characteristics, drug loading, in vitro release profile and their applications in delivery of drug molecules and therapeutic genes.
12 March 2012

A COMPARATIVE RELEASE STUDY OF ZIPRASIDONE HYDROCHLORIDE MONOHYDRATE FROM DIFFERENT VEHICLES BY USING DIFFERENT CHEMICAL ENHANCERS

ABOUT AUTHORS:
RANI SHALU^1*, SAROHA KAMAL¹, NANDA SANJU²
¹Institute of Pharmaceutical Sciences,
Kurukshetra University, Kurukshetra 136119, Haryana, India.
²Department of Pharmaceutical Sciences,
MDU, Rohtak 124001,
Haryana, India.

ABSTRACT
The aim of the present study was to investigate the in-vitro release properties of Ziprasidone hydrochloride monohydrate from different topical vehicles. By the unique advantages over the traditional drug delivery, transdermal drug delivery is becoming increasingly important and has got a vital interest in pharmaceutical industries. An in vitro release experiment was designed to reveal the rate of release of ziprasidone hydrochloride monohydrate from four different topical vehicles: (i) cream; (ii) a gel; (iii) an ointment (iv) pronoisomal gel. In vitro release of ziprasidone hydrochloride monohydrate from the four bases was monitored spectrophotometrically at a wavelength of 318 nm. In vitro release study results showed that the release of drug from vehicles ranks according to the following order: gel> proniosomal gel> cream> ointment. Gel base showed considerably higher drug release than other vehicles. Five types of chemical enhancers was used in the study and among them tulsi oil was the best enhancer. As we increase the concentration of chemical enhancer the release of drug also increases. By monitoring and attempting to explain the many possible reasons for the different rates of drug release from the vehicles, it was hope that the experiment would confer essential information concerning factors affecting the release of drugs from topical formulations.
11 November 2011

Multiplace vacancies in Ahlcon Parenterals India | Require Sales Manager, Tewrritory Sales Manager
25 October 2011

Walk-in: Opening for Project Fellow in Maharshi Dayanand University

Maharshi Dayanand University, ab initio established as Rohtak University, Rohtak, came into existence by an Act No. 25 of 1975 of the Haryana Legislative Assembly in 1976 with the objective to promote inter-disciplinary higher education and research in the fields of environmental, ecological and life sciences.