Mysore

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF 2, 4 - DISUBSTITUTED QUINOLINES

About Authors:
Md. Sofiqul Islam, Madhusudan N. Purohit
Department of Pharmaceutical Chemistry,
JSS college of Pharmacy, Mysore 570015

Quinoline and its derivatives are well  known for their antimalarial and antibacterial propertites. A number of quinoline derivatives are known to possess antimicrobial, antitumor, antifungal, hypotensive, anti HIV, analgesics and anti-inflamatory activites. Application of quinoline derivative are fast spreading from antimalarial drugs to almost every branch of medicinal chemistry. Substitution of halogen group in a suitable position of a bioactive molecule is found to exert a profound pharmacological effect.

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