Varanasi

RATIONAL OF ANIMALS USE IN DRUG DISCOVERY

ABOUT AUTHORS:
Aruni Kumari, Ajit Kumar Thakur, Vikas Kumar*
Neuropharmacology Research Laboratory, Department of Pharmaceutics,
Indian Institute of Technology (Banaras Hindu University),
Varanasi-221 005, India
*vikas.phe@iitbhu.ac.in

ABSTRACT
Animals play a pivotal role in science and scientific technology. All the animals used in experiments are treated ethically following legislative rules. Small animal such as mice, turtles, frogs, rats etc. are used which has short span of reproductive cycle. Their population can be multiplied within six months. The use of animals in research is analyzed from the viewpoint of three distinct ethical approaches: contractarianism, utilitarianism and animal rights view. On contractarian point of view, research on animal is ethical to the extent that human as a social party should care about its well being. According to utilitarian point of view, harm caused to the sentient animal during research should be compensated with benefit to human society. From the animal rights view, use of animals in science is not in animal’s best interest. In this review, comprehensive information is provided on contribution of animal research in drug discovery and development.

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