Mehsana

Pharma Courses
  • PharmaTutor
    22 November 2013

    Looking for Operator -Tablet compression and coating machine in PAR Laboratories

    PAR Laboratories is an industry leader in the development and marketing of hormonal products.. All of PAR Laboratories products are manufactured to the highest standards of quality and supported by exceptional customer care professionals. PAR has a fully dedicated Research and Development facility in Navi Mumbai that ensures a robust and a continuous pipeline of quality products. The Company markets its products to drug wholesalers, retail drug chains, pharmaceutical distributors, hospitals, clinics and government agencies worldwide.

    Post: Operator - 1

  • 12 November 2013
    Work as Professional sales representative in Dominant Pharma

  • 10 October 2013
    Job for B.Pharm, B.Sc as Area manager in Leading for Pharma Company | Nextus Solution

    A renowned name, NEXTUS SOLUTIONS is a professionally managed organization engaged in offering highly acclaimed consultancy, Training and Placement. With our in- depth expertise and rich experience in the wide range of fields in India and abroad, we adopt a systematic and straightforward approach with every assignment of work we undertake. The effectiveness of our systematic and results-focused approach is reflected in our many long-term client relationships.

  • 9 October 2013
    Opportunity for B.Pharm, M.Pharm, M.Sc as QA Officer in PAR Laboratories

    As a dedicated manufacturer and marketer of Hormone products, the Company concentrated on the niche areas of operations. With its beginnings in Mumbai, PAR Laboratories has been providing quality hormones and contraceptive products to various markets around the world.
    In recent months, the Company has been transitioning to position itself for a substantial growth. PAR Laboratories’ acquisition by another pharma group with vast International experience opened the doors of the company to many markets. Along with it came the access to the group’s complete Research and Development facility in Navi Mumbai. This is quickening our ability to bring new hormonal products and better formulations to the market place rapidly. Over the years, PAR Laboratories has been able to identify several new product opportunities which are now in a state of development and continuous improvements.

    Post: QA Officer - 2

  • 9 October 2013
    Opening for B. Pharm, M.Pharm as Regulatory Affairs Officer (2 posts) in PAR Laboratories

    As a dedicated manufacturer and marketer of Hormone products, the Company concentrated on the niche areas of operations. With its beginnings in Mumbai, PAR Laboratories has been providing quality hormones and contraceptive products to various markets around the world.
    In recent months, the Company has been transitioning to position itself for a substantial growth. PAR Laboratories’ acquisition by another pharma group with vast International experience opened the doors of the company to many markets. Along with it came the access to the group’s complete Research and Development facility in Navi Mumbai. This is quickening our ability to bring new hormonal products and better formulations to the market place rapidly. Over the years, PAR Laboratories has been able to identify several new product opportunities which are now in a state of development and continuous improvements.

    Post: Regulatory Affairs Oficer - 2

  • 19 August 2013
    Walk in interview for Medical Representative in Ajanta Pharma

    Ajanta Pharma Limited is an emerging, global pharmaceutical company with proven capabilities in the areas of product research, manufacturing & marketing.

  • 11 August 2013
    Vacancies for Regional Sales Manager, Field Sales Manager, Medical Representative in Juggat Pharma

    We are happy to invite you to scale new career heights in healthcare & pharmaceutical sales and marketing. Jagdale Lifesciences - the lifesciences division of Jagdale Industries Ltd., Bangalore, offers excellent openings for interested suitable candidates in sales and marketing. Jagdale Lifesciences is the sister division of Juggat Pharma, Bangalore, which is the flagship division of JIL. The key Juggat Pharma brands include Botropase, BotroClot, ORS-L, and Dart.

  • 30 July 2013
    H2S : REVOLUTIONARY SCIENTIFIC MIRACLE AS A GASOTRANSMITTER AT MAXIMUM POTENTIAL IF USED WISELY

    ABOUT AUTHORS:
    Krishna J. Kathawala1*, Gaurav L. Ninama1, Ankitkumar Y. Parikh1, Krupali V. Upadhyay2
    1A. R. College of Pharmacy & G. H. Patel Institute of Pharmacy B/H. B & B Polytechnic College, Vallabh Vidyanagar - 388 120, Gujarat, India.
    2Shree Satsangi Saketdham “Ram Ashram” group of Institution, At. & Post. Vadasma, Tal. & Dist. Mehsana, Gujarat – 382708, India.
    *krishna.kathawala@gmail.com

    ABSTRACT
    Nitric oxide (NO) and Carbon monoxide (CO) are the reputed neurotransmitters involved in the regulation of vascular tone. H2S, which synthesized from L-cysteine, can play more vital role as Gasotransmitters compare to NO and CO. H2S have a role as a stimulator of ATP-sensitive potassium channels (KATP-channels) in the vascular smooth muscle cells, neurons, cardiomyocytes and pancreatic β-cells. H2S also minimize the toxic effect by reacting with reactive oxygen and/or nitrogen species and attenuating their physiological functions. H2S have a unique feature of not to stimulate soluble guanylate-cyclase like other Gasotransmitters. H2S plays a critical role in the regulation of vascular tone, neurotransmission, insulin secretion, and myocardial contractility. Recent studies showed that, in various animal models of arterial and pulmonary hypertension, Alzheimer’s disease, gastric mucosal injury and liver cirrhosis had H2S deficiency which defines the significance of H2S. Exogenous H2S alleviates myocardial dysfunction associated with the ischemia/reperfusion injury with reducing the damage of gastric mucosa generated by anti-inflammatory drugs. H2S had also some drawbacks like every coin has two sides. Excessive production of H2S may contribute to the pathogenesis of inflammatory diseases, septic shock, cerebral stroke and mental retardation in patients with Down syndrome, and reduction of its production may be of potential therapeutic value in these states. Preclinical evidence is provided to show that H2S releasing derivatives of several NSAIDs, including Diclofenac and Indomethacin indeed represent excellent gastrointestinal safety and are more potent than the parent drugs as anti inflammatory agents. Derivatives of anti-inflammatory drugs other than NSAIDs (e.g. mesalamine) have also been shown to be significantly improved over the parent drug in many respects. So, H2S can be Revolutionary scientific miracle as a gasotransmitters  at maximum potential if the drawbacks are minimize by cutting edge solution.

  • 8 April 2013
    RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF MONTELUKAST SODIUM AND DESLORATADINE IN COMBINED DOSAGE FORM

    ABOUT AUTHORS:
    Rima M. Bankar*, Dipti B. Patel
    Department of Pharmaceutical Analysis,
    Shree S. K. Patel College of Pharmaceutical Education & Research, Ganpat University,
    Ganpat Vidyanagar – 384012, Mehsana, Gujarat, India.
    *rima.banker@yahoo.com

    ABSTRACT
    A novel, precise, accurate and rapid isocratic reversed-phase high performance liquid chromatographic/ultraviolet (RP-HPLC/UV) method was developed, optimized and validated for  simultaneous determination of Montelukast Sodium and Desloratadine. The method showed adequate separation for Montelukast Sodium and Desloratadine  and best resolution was achieved with ACE 5 C18 column (150 mm × 4.6 mm i.d, 5 μm particle size) using Acetonitrile-Methanol-Water (15:80:5, v/v) as a mobile phase at a flow rate of 1.0 ml/min and wavelength of 283 nm. The calibration curves were linear over the concentration ranges of 5-50 μg/ml for Montelukast Sodium and Desloratadine. The limit of detection (LOD) and limit of quantification (LOQ) for Montelukast Sodium were 0.33 and 1.01 μg/ml while for Desloratadine were 0.10 and 0.31 μg/ml, respectively. All the analytes were separated in less than 6.0 min. The proposed method could be applied for routinelaboratory analysis of Montelukast Sodium and Desloratadine in pharmaceutical dosage form. Methods were validated statistically and recovery studies were carried out. The proposed methods have been applied successfully to the analysis of cited drug either in pure form or in synthetic mixture of both drugs with good accuracy and precision. The method herein described can be employed for quality control and routine analysis of drugs in pharmaceutical formulations.

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  • 4 April 2013
    SIMULTANEOUS ESTIMATION OF EPERISONE HYDROCHLORIDE AND DICLOFENAC SODIUM BY RATIO SPECTRA DERIVATIVE SPECTROPHOTOMETRY METHOD IN SYNTHETIC MIXTURE

    ABOUT AUTHORS:
    Rinku B Patel*1, Paresh U Patel2, Bharat G Patel3, Anil C Patel2
    1Department of Pharmaceutical Analysis, Centre For Health Science Studies, Ganpat University, Ganpat Vidyanagar – 384012, Mehsana, Gujarat, India.
    2Department of Quality Assurance, Centre For Health Science Studies, Ganpat University, Ganpat Vidyanagar – 384012, Mehsana, Gujarat, India.
    3Aspee college of Home Science and Nutrition, S.D.Agricultural University, S.K.Nagar-385506, Banaskantha, Gujarat, India.
    *rinkupatel5890@gmail.com

    ABSTRACT
    Simple, accurate, precise, and sensitive ratio spectra derivative spectrophotometric method for simultaneous estimation of Eperisone hydrochloride (EPE) and Diclofenac sodium(DIC) in synthetic mixture have been developed and validated. The ratio derivative spectroscopic method involves measurement of first derivative amplitude of ratio spectra at 247 nm for EPE and 218.4 nm for DIC as two wavelengths for estimation. Beer's law is obeyed in the concentration range of 2-18 μg/ml for both EPE and DIC. LOD values for EPE and DIC are found to be 0.0634 μg/ml and 0.5386 μg/ml, respectively. LOQ values for EPE and DIC are found to be 0.1921 μg/ml and 1.6321 μg/ml, respectively. The method was validated statistically and recovery studies were carried out. It was found to be accurate, precise and reproducible. The method was applied to the assay of the drugs in synthetic mixture, which were found in the range of 98.0% to 102.0% of the labeled value for both Eperisone hydrochloride and Diclofenac sodium. Hence, the method herein described can be successfully applied in quality control of synthetic mixture.

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