Maharashtra

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ABOUT AUTHORS:
Shete Reshma S.¹*, Gadhave Manoj V.², Gaikwad D. D.^3
1Department of Quality Assurance Techniques,
²Department of Pharmaceutics,
³Department of Pharmaceutics,
VJSM’S Vishal institute of pharmaceutical education and research, Ale, Pune, Maharashtra, 412411
*reshma.s.shete@gmail.com

ABSTRCT
Simvastatin is a poorly soluble drug exhibiting poor dissolution pattern. Simvastatin, PEG 6000 & Poloxamer 407 solid dispersions were prepared with a view to study the influence of polymer on solubility and dissolution of this poorly soluble drug Simvastatin. Solid dispersions of Simvastatin were prepared using different ratios of PEG 6000 & Poloxamer 407 as carrier by, solvent evaporation method. They were evaluated for percentage yield, drug content, FTIR spectral studies, DSC, XRD, solubility, and in-vitro dissolution. The solubility profile indicated that there is increase in solubility of Simvastatin when polymer concentration is increased. The solid dispersion complex of drug (1:5:5 ratios) was giving better dissolution profile as compared to pure drug and other solid dispersions. This in turn can improve the bioavailability. FT-IR, DSC shows the compatibility of drug and carrier.

Welcome to Kalyan Dombivli Municipal Corporation Enterprise Information Portal (KDMC-EIP). In our endeavor to offer quality Citizen Services, we are now happy to bring the Corporation at your finger tips through this portal. We are sure that the citizen of the new age will draw immense benefits from the new Point & Click KDMC.

Post: Pharmacist

Applications are invited from eligible candidates for the following posts to be filled in College’s M.Pharmacy section.

Post: Professor, Associate Professor, Assistant Professor

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No.of post: 03

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC, Kharghar, Navi Mumbai is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer. TMC is an autonomous grant-in-aid institution of the Department of Atomic Energy (DAE), Government of India. It is registered under the Societies Registration Act (1860) and the Bombay Public Trust Act (1950). Its Governing Council is headed by the Chairman, Atomic Energy Commission, Government of India.

U S Pharma (I) is a niche player in the pharmaceutical formulation market with a focus on exports only. We have 4 sections namely tablets, capsules, liquid oral and ointments. We are based near the Cocacola factory at Kudus on the Bhiwandi-Wada highway.

Post: Manufacturing Chemist

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ABOUT AUTHORS:
Auti Snehal D.*¹, Jadhav S. L², Gadhave Manoj V^3
1Department of Quality Assurance Techniques
^2,3Department of Pharmaceutics
VJSM’S Vishal institute of pharmaceutical education and research, Ale, Pune, Maharashtra, 412411
snehal.d.auti@gmail.com

ABSTRACT:
The present research work discusses the development of a dissolution method for Fluconazole using UV spectrophotometer. Simple, accurate and cost efficient dissolution method has been developed for the estimation of Fluconazole in bulk and tablet dosage form. The optimum conditions for the dissolution of the drug were established. The dissolution media was found to be 0.1N HCl (pH 1.2). The apparatus was found to be USP II, Paddle and the speed was found to be 50 rpm for 30 minutes time interval.

MSACS envisions an India where every person living with HIV has access to quality care and is treated with dignity. Effective prevention, care and support for HIV/AIDS is possible in an environment where human rights are respected and where those infected or affected by HIV/AIDS live a life without stigma and discrimination.

Post: Pharmacist. (ART Center, Medical College Vishnupuri & for WL)