Skip to main content

Tamil Nadu

  • Govt of India invites Pharmacists @ CISF

    The CISF came into existence in 1969 with a modest beginning, having three battalions, to provide integrated security cover to the Public Sector Undertakings (PSUs) which, in those years, occupied the “commanding heights” of the economy. In a span of four decades, the Force has grown several folds to reach one lakh twelve thousand personnel today.

  • FORMULATION AND EVALUATION OF CLARITHROMYCIN IMMEDIATE RELEASE FILM COATED TABLETS

    About Authors:
    S. H. Seyed Mohamed Buhary*, Kamarapu Nagaraju, A. Thanga Thirupathi.
    Department of Pharmaceutics, Sankaralingam Bhuvaneswari College of Pharmacy,
    Sivakasi, Tamil Nadu, India.
    * nagarajukamarapu8@gmail.com

    ABSTRACT:
    The main goal of this study was to develop a stable formulation of antibiotic drug clarithromycin as an immediate-release tablet. The task of developing immediate release tablet is accomplished by using a suitable diluents and super-disintegrants. Faster disintegration of the tablet administrated orally minimizes absorption time and improves its bioavailability in less time.   The formulation development work was initiated with wet granulation. Microcrystalline cellulose PH 102 were used as diluent. Povidone was used as the binder. Croscarmellose sodium and pre gelatinized starchwas added as a disintegrating agent. Talc and magnesium stearate was used as the lubricant. The prepared granules were compressed into a compression machine.  To evaluate the formulated tablets as per requirements of standards. The tablets thus formulated showed  a satisfactory physical parameters, and it was found to be stable.Evalution Parameters Like weight variation, hardness of the tablet, friability, thickness, disintegration test, drug content uniformity and in vitro release studies were performed.To optimize the trial batch by    32 full factorial design study and determined  the best batch by in vitro release studies are showed that  optimization formulation (OF7) was 101.62% respectively. The  optimized formulation is further selected and compared with the release profile of the innovator product. The results suggest the feasibility of developing immediate  tablets consisting of clarithromycin for the convenience of patients with respiratory infections, gonorrhea, community-acquired pneumonia, pelvic inflammatory disease, pediatric otitis media and pharyngitis and Mycobacterium avium complex (MAC) in patients with advanced HIV disease.

    [adsense:336x280:8701650588]

  • OVERVIEW ON: ATTRITION IN PHARMACEUTICAL MARKETING, CAUSES AND ITS MEASURES

    About Authors:
    Jeevan Sharma1*, Davidson Rajesh2
    1B.Pharmacy, JSS college of pharmacy Ooty
    2Regional manager, Natco Pharma litmited, Chennai
    *jeevan.pharma@yahoo.com

    ABSTRACTS:
    Attrition refers to the reduction in staff and employees in a company through normal means, such as retirement and resignation. The primary focus of this  article is to present the high rate of attrition seen in the pharmaceutical marketing  industry , its causes and controlling strategy for  retentions of pharma sales representatives. Though  attrition is a natural phenomena in all industries  , Indian Pharma marketing industries is worst plagued by It. After IT and BPO , pharma  marketing industries experience  the greatest rate of employee leaving the company for various reasons. While   global pharma  marketing attrition rate  is  10-12%  per annum, the rate of employees who leave  the organization in India is 25 -30 %.  The attrition is more prevalent in the middle and junior management level.

  • Working opportunity in NATIONAL FACILITY ON DRUG DEVELOPMENT (NFDD) as Research Associate, JRF, Project Assistant

    Applications are invited for the various research positions (Purely Temporary) for the DST, New Delhi sponsored National Facility on Drug Development for Academic Institutions, Pharmaceutical and Allied Industries in Regional Office, Anna University, Chennai, BIT Campus, Tiruchirappalli – 620 024.

    Post: RESEARCH ASSOCIATE, JRF, PROJECT ASSISTANT

  • Madras Medical Mission opens for Pharmacist

    Madras Medical Mission is an organization inspired by the missionary zeal of Bishop Zachariah Mar Dionysius, Metropolitan of the Madras Diocese of the Orthodox Church of India.

  • Urgent requirement in RANBAXY for Medical Representative in ADILABAD, BOBBILI, NARSARAOPETA, HQs

    FOR MEDICAL REPRESENTATIVE JOBS *URGENT REQUIREMENT IN ‘RANBAXY MAXXIM’ FOR ADILABAD, NARSARAOPETA, BOBBILI HQS .

    Post: TERRITORY EXECUTIVE

    [adsense:336x280:8701650588]

  • QUANTITATIVE DETERMINATION OF ASENAPINE MALEATE USING REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

    About Authors:
    T.R.PARTHASARATHI*, M.VANITHA SRI.
    BIOANALYTICAL DEPARTMENT,
    QUEST LIFE SCIENCES PVT. LTD, SDF III, MEPZ,
    TAMBARAM, CHENNAI- 600 045, INDIA.
    *parthu_14@yahoo.co.in

    ABSTRACT :
    A novel isocratic reverse-phase high performance liquid-chromatography method for determination of asenapine maleate was developed and validated after optimization of various chromatographic conditions. Samples were separated on a waters x-terra C18 (100 mm × 4.6 mm, 3.5 μ) analytical column. The mobile phase used was acetonitrile: 0.1M phosphate buffer (pH 3.2) 65:35%v/v operated at 30 °C column oven temperature was pumped at a flow rate of 1.0 mL min−1 and the column eluents were monitored at a wavelength of 272 nm. When sample was injected into the Finnigan surveyor high performance liquid-chromatography system through Finnigan surveyor auto-sampler injector, separation was achieved within 5.0 min. The present method demonstrated was validated with the acceptable values for selectivity, linearity (within the expected concentration range (10–50 μg mL−1; r2 > 0.999)), recovery (>95%), precision (%RSD < 2.0), sensitivity (limit of detection: 1.85 µg mL−1 and lower limit of quantification: 2.34 µg mL−1), robustness, and ruggedness.

  • Annamalai University invites Junior Research Fellow in Department of Botany

    The Department of Botany, Annamalai University is well known renowned department in teaching and research. The department is UGC sponsored and FIST dept with good record of quality research in the field of plant science

    POST: JRF (Post 1)

    [adsense:336x280:8701650588]

  • Synthesis and characterization of gelatin nanoparticle from fish and it role as drug delivery vehicle for Tuberculosis

    About Authors:
    L.Kalaiselvi1*, Mr.R.Ulaganathan2
    1
    B.Pharm, II M.Tech Nanoscience&Technology,
    2 Assistant Professor, B.Sc, M.Sc., M.Tech
    Department of Biotechnology, Udaya school of Engineering,
    Nagercoil, Kanyakumari dt.
    *klkselvi@gmail.com

    ABSTRACT:
    Nanoparticle based systems have significant prospective for diagnosis, treatment and prevention of tuberculosis (TB) Gelatin nanoparticle derived from marine sources (fish skin, bone and fins) has been looked upon as a possible alternative to bovine and porcine. Fish gelatin nanoparticle synthesis by two step desolvation method, it was stable nanoparticles and confirm through Scanning electron microscopy (SEM).These nanoparticle were used as carrier for rifampicin. Our aim to develop a Nano particulate carrier of rifampicin for controlled delivery as well as reduced toxicity. In this study, rifampicin loaded fish gelatin nanoparticle was fabricated by an absorption/adsorption method. The effect of several variables on the Nanoparticle’s characteristics was calculated.

  • Filling up of posts of Technical/ Scientific services of Food Safety and Standards Authority of India - 32 posts

    The Food Safety and Standards Authority of India (FSSAI) is an autonomous statutory Authority set up under the Food Safety and Standards Act, 2006 for laying down science based standards for articles of food and to regulate their manufacture, storage, distribution, sale and import to ensure availability of safe and wholesome food for human consumption.

Subscribe to Tamil Nadu