Tamil Nadu

Shasun Pharmaceuticals invites for Sales Officers, Area Managers through Walk in Interview

Shasun Pharmaceutical Division develops and manufactures formulations for solid dosage products. Shasun Pharmaceutical Division develops and manufactures formulations for solid dosage products. The Division is a vertically integrated formulations partner for the pharmaceutical industry. Its services include formulation research and development activities, Analytical method development and validation, scale-up and technology transfer, clinical supplies manufacturing to full scale commercial manufacturing of oral solid dosage forms.

Require Business Development Officer in EPIDermizz, a skincare division of Nippon Seiyaku

EPIDermizz, a skincare division of Nippon Seiyaku Pvt. Ltd. Nippon Seiyaku Pvt. Ltd. is an associate of Nippon Seiyaku co. Ltd., Japan which have been started its operation in Indian Market in 2001. Having robust brand NUTRIFACTS, Nippon is one of the most admired companies in pediatric fraternity. It has the history of pioneering in the area of nutrition by launching molecules like Methylcobalamine, Benfothiamine and Co Enzyme Q10 first time in India.

ANTI CANCER POTENTIAL OF TECOMA STANS FLOWER EXTRACT

About Authors:
S.Kameshwaran1*, V.Suresh1, M.Mohanraj2
1Department of pharmacology,
JKK munirajah medical research foundation and College of Pharmacy,
B.Komarapalayam, Namakkal, Tamilnadu - 638183
2Marineboitoxinology labs, CAS in marine biology, Annamalai university,
Chidambaram, Tamilnadu-608502
*kamesh.pharm@gmail.com

ABSTRACT
Tecoma stans flowers have been traditionally used for many ailments including cancer. In the present study, anti cancer activity of methanolic flower extract of T.stans (METS) was evaluated using both in vitro and in vivo methods. METS was subjected to preliminary qualitative phytochemical investigations by using standard procedures. In vitro antitumor activity of METS was evaluated by the MTT assay methodusing Vero and HEP-2 cell lines. Then the extract subjected to in vivo anti cancer activity using Ehrlich ascites carcinoma (EAC) tumor model. The activity was assessed Increase in life span, average increase in body weight, changes in food intake, tumor volume, tumor weight, viable cell count, non viable cell count, PCV, Total cell count and hematological studies. The potency of the extract was compared with standard 5-flurouracil (20 mg/kg i.p.).In in vitro anti cancer activity METS exhibited significant cytotoxic activity against both cell lines even at different concentrations. Oral administration of METS at the dose of 200 and 400 mg/Kg, significantly (p < 0.001) increased the survival time, non viable cell count and decreased the average body weight and food intake, viable cell count of the tumor bearing mice. After 14 days of inoculation, METS was able to reverse the changes in the hematological parameters, protein and PCV consequent to tumor inoculation.The results indicate that METS possess significant antitumor activity on dose dependent manner.

Opportunity to work as DRUGS INSPECTOR, JUNIOR ANALYST in the Drugs Testing Laboratory, Phenyle Assistant in TNPSC - Total 114 posts | Freshers - last date to apply

Applications are invited only through online mode upto 12.04.2012 for Direct Recruitment to the vacancies in the following posts:-

POST: Drugs Inspector, Junior Analyst in the Drugs Testing Laboratory, Phenyle Assistant

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