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  • Stevia rebaudiana : a ray of life for diabetics

    Stevia rebaudianais a well known medicinal herb contains antibacterial, antifungal, anti-inflammatory, anti-viral, anti-yeast, cardiotonic diuretic and hypoglycaemic properties. This herb has been used in Ayurveda in India since centuries. Stevia is a perennial herb belonging to the family Asteraceae, is one of the most valuable tropical medicinal plant. Leaves of this plant produce zero calorie, high potency sweetener and substitute to sucrose, being about 300 times sweeter than sucrose. The compounds, named stevioside and rebaudiocide give stevia its taste. In India number of diabetic people in the age group of 25-45 is about 15% and is also increasing at an alarming pace. In addition, India is the largest consumer of sugar in the world. So stevia is attaining attention in Indian market as a healthy alternative sweetener to sugar. Stevia has no calcium cyclamate, no saccharim, no aspartame and no calories. It is safe for diabetics, as it does not affect blood sugar levels and have no neurological or renal side effects.

  • A PRIMER ON QUALITY AND SAFETY OF COSMETICS

    About Author:
    Tarun Patel, Prof. Dr. Vipin Kukkar, Amit Patel

    Seth G.L. Bihani S.D. College of Technical Education,
    Institute of Pharmaceutical Sciences and Drug Research,
    Sri Ganganagar, Rajasthan, INDIA

    ABSTRACT:
    It is a product which is used for improvement of appearance of human body by applying it externally on human body. For better results and minimizing risk of adverse reaction of cosmetic products on human body we have to check out and maintain quality of cosmetic products during its manufacturing.  And  also required some safety parameters for manufacturing of cosmetic products. In this review article we discussed briefly about quality and safety parameters during manufacturing of cosmetic products.

  • MOBILE TECHNOLOGY IN HEALTHCARE

    Mobile technology is defined as a term which includes all types of communications performed by mobile. These days mobile health or mHealth is an emerging field which uses mobile technology to deliver better healthcare services and also useful in health researches which helps to meet the global health challenges of today.

  • FORMULATION AND EVALUATION OF ITRACONAZOLE TRANSDERMAL PATCHES

    About Authors:
    Sreedhar Reddy C
    M.Pharm, Department of Pharmaceutics,
    Vasavi Insitute of Pharmaceutical Sciences,
    Vasavi Nagar, Peddapalli (V), Kadapa (dist),
    A.P, India

    Abstract:
    In this study, transdermal patches containing Itraconazole were prepared using different ratios of polyvinylpyrrolidone (PVP) and Hydroxy propyl methyl cellulose (HPMC) by solvent evaporation technique using 10%w/w of dibutyl phthalate incorporated as plasticizer. The drug matrix film of PVP and HPMC was casted on a polyvinylalcohol backing membrane that was previously dried at 600C for 6 hrs. All the prepared formulations were subjected to physical studies (moisture content, moisture uptake, Tensile strength, flatness and Drug content determination), in vitro release studies and in vitro skin permeation studies. The physiochemical compatibility of the drug and the polymers studied by IR spectroscopy have absence of any incompatibility. In vitro permeation studies were performed across  skin using a Franz diffusion cell. Variations in drug release profiles among the formulations studied were observed. Based on a physicochemical and in vitro skin permeation study, formulation F1 (PVP/HPMC, 5:1) and F5 (PVP/HPMC, 1:5) were chosen for further in vivo experiments. The anti inflammatory effect and a sustaining action of Itraconazole from the two transdermal patches selected were studied by inducing paw edema in rats with 1% w/v carrageenan solution. Hence, it can be reasonably concluded that Itraconazole can be formulated into the transdermal matrix type patches to sustain its release characteristics.

  • Corporate Environmental Responsibility of Indian Pharma Companies

    The Indian Pharmaceutical Industry today is in the front rank of India’s science-based industries with wide ranging capabilities in the complex field of drug manufacture and technology. It ranks very high in the third world, in terms of technology, quality and range of medicines manufactured. From simple headache pills to sophisticated antibiotics and complex cardiac compounds, almost every type of medicine is now made indigenously.

  • Naming of Drug Molecules and Pharmaceutical Brands

    About Authors:
    Dr. Amit Gangwal,
    Smriti College of Pharmaceutical Education,
    Indore

    Abstract
    For running any business or organization their products or services should be of utmost quality keeping other things aside. These products or services are known in commerce by their names. These names are called brand names and these are assigned by the owner or innovator or researcher or sponsor of that product or service depending on the type of produce and various parameters. Though company introduces the brand in commerce but after its (brand’s) establishment, brand becomes the identity of company. Brand names are most important attribute of a product after its quality and packing from end user’s (customer) point of view. Successful brand names never escape from the memory of consumer. Few such brand names are Bislery, Maggi, Vicks, Surf Excel, Coca-Cola, Google etc. Few reputed and well known pharmaceutical brands are Corex, Lipitor, Gleevac, Viagra etc. In present article various process to name a drug and a pharmaceutical formulations’ name (brand name) have been described. Article throws light on generic, chemical and brand names of a drug or formulations besides few case studies and guidelines.

  • University of Pune Sponsored Conference on CURRENT TRENDS IN cGMP AND REGULATORY REQUIREMENTS at R.G Sapkal College of Pharmacy

    Ravindra Gambhirrao Sapkal College of Pharmacy is started in 2008-09. Institute caters Degree course in Pharmacy and Post graduate course in Quality Assurance Techniques. Since its inception institute is striving hard for budding pharmacist. In addition to a well-structured yet flexible curriculum, our institute provides ample opportunity for active research collaborations with phama industries to equip our students to develop a strong set of competencies desired in todays hypercompetitive world.

  • WHO and the International Pharmaceutical Federation (FIP) signed a Joint Statement on the role of PHARMACISTS in tuberculosis care and control

    At the Federation's 71st International Congress in Hyderabad, India, the World Health Organization (WHO) and the International Pharmaceutical Federation (FIP) signed a Joint Statement on the role of pharmacists in tuberculosis care and control

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  • BRAIN TARGETING NOVAL APPROACHES: A COMPREHENSIVE REVIEW

    About Authors:
    Sandhu Premjeet1, 2,Rathore Devashish2, Kataria Sahil1 , Middha Akanksh1
    1Seth G. L. Bihani S.D. College of Technical Education,
    Institute of Pharmaceutical Sciences and Drug Research,
    Sri Ganganagar, Rajasthan, INDIA
    2 School of Pharmaceutical Sciences, RGPV University campus,
    Bhopal, M.P, INDIA

    ABSTRACT
    The blood – brain barrier (BBB) has always presented a challenge to scientists for brain drug targeting . the BBB evolved in such a way that it protects the brain from various foreign substance such as neurotoxins. This mechanism makes the BBB an insurmountable . This mechanism makes BBB an insurmountable barrier for numerous highly essential drugs , including antibiotics, cytostatics and other CNS active drug Drugs may be administered directly into the CNS or administered systematically (e.g. by intravenous injection) for targeted action in the CNS. The major challenge to CNS drug delivery is the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. Various strategies that have been used for manipulating the blood-brain barrier for drug delivery to the brain include osmotic and chemical opening of the blood-brain barrier as well as the use of transport/carrier systems. Other strategies for drug delivery to the brain involve bypassing the BBB. Various pharmacological agents have been used to open the BBB and direct invasive methods can introduce therapeutic agents into the brain substance. It is important to consider not only the net delivery of the agent to the CNS, but also the ability of the agent to access the relevant target site within the CNS. Various routes of administration as well as conjugations of drugs, e.g. with liposomes and nanoparticles are considered. Some routes of direct administration to the brain are non-invasive such as transnasal route whereas others involve entry into the CNS by devices and needles such as in case of intrathecal and intracerebroventricular delivery.

  • Transdermal Drug Delivery System- A Total View

    About Authors:
    Vinay Mishra, Shilpi Bhargava
    Advance Institute of Biotech and Paramedical Sciences,
    Kanpur

    Introduction:
    Delivering medicine to the general circulation through the skin is seen as a desirable alternative to taking it by mouth. Patientsoften forget to take their medicine, and even the most faithfullycompliant get tired of swallowing pills, especially if theymust take several each day. Additionally, bypassing the gastrointestinal(GI) tract would obviate the GI irritation that frequently occursand avoid partial first-pass inactivation by the liver. Further,steady absorption of drug over hours or days is usually preferableto the blood level spikes and troughs produced by oral dosageforms.1

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