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  • A hand-held, miniature microscope roughly the size of a pen can allow surgeons to "see" at a cellular level in the operating room and determine where to stop cutting the tumour to kill only cancerous cells and protect healthy cells.

  • Agenus Inc., an immuno-oncology company developing checkpoint modulator antibodies and cancer vaccines, announced  that the U.S. Food and Drug Administration (FDA) cleared the company's investigational new drug (IND) application for AGEN1884, an immune checkpoint modulator (CPM) antibody that binds to cytotoxic T-lymphocyte antigen-4 (CTLA-4). Clearance was also received for a second CPM antibody partnered with Incyte (NASDAQ: INCY) for INCAGN1876, which targets glucocorticoid-induced TNFR-related protein (GITR). Clinical trials for both candidates are expected to begin in the first half of 2016.

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