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Workshop on Recent trends in structural biology & drug designing organised by Biotech Park, Lucknow

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Designing and developing a new drug molecule is increasingly becoming a time and cost intensive process, which has limited the rate of drug discovery and very few new molecules are reaching into the market. Computational methods have been in use for various forms of drug discovery like QSAR, Molecular Simulations, Molecular Docking, Virtual Screening and Structure-based drug designing methods for some time. Drug Designing is the inventive process of finding new medications based on understanding of the biological target. Today the in-silico approaches permits to address most of the key steps of drug discovery such as designing the drug, identifying the target, aligning the sequences for structure prediction, understanding its binding, determining the efficiency and stability of drug enzyme complex. The knowledge of protein functions is important as they play a crucial role in determining the nature and function of body as well as in the diseases process. Structural biology encompasses recombinant protein technologies, macromolecular structure determination and computational biomolecular sciences applied to membrane proteins, supramolecular assemblies and molecular interactions. Structural biology provides a view of life at the molecular and atomic levels. The high-resolution structures of proteins, DNA, RNA, and small molecules are the "blueprints" for both the structure and function of cells. They can reveal intricate detail how enzymes catalyze reactions, how cells receive signals from the outside, or how genes are turned on and off during development. High-resolution structures can also reveal how mutations can have disastrous effects on normal cellular function, often leading to cell death or to uncontrolled cell growth and cancer.

The workshop aims:
Acquaint the participants with applications of bioinformatics in drug discovery process.
To familiarize participants with topology coordinates identification, in-silico target molecule properties evaluation.
To apprise the participants with the recent methods of molecular dynamics simulations which lead to the successful design of proficient, precise and non-toxic small-molecules through guided practical training.

Objectives
The participants of the workshop will be accessing offline and online resources of macromolecule libraries, molecular docking, molecular simulations and novel drug discovery. They would also learn about prediction and analysis of various properties of compounds, bimolecular structure prediction, visualization, interaction analysis and Pharmacophore designing. The practical knowledge gained through this hands-on workshop will empower participants in the field of in-silico drug development methods and enhance their employment potential in academia and industrial research.

Topics to be covered
The workshop will consist of lectures, group discussions, case studies, exchange & sharing of experience on:

  • Bioinformatics and its application
  • Biological Databases
  • Functional Genomics and Proteomics
  • Structural Bioinformatics
  • Proteins 3-D Structure Prediction
  • Drug Designing & Case study
  • Science involved in disease target identification
  • Pocket/ Active site identification
  • Lead identification and optimization
  • In-silico generation of novel ligand molecules
  • Target ligand docking
  • 3-D Quantitative Structure Activity Relationships
  • Rational drug discovery

Who should attend?
Scientists / Research fellows (National Laboratories & Universities) and Graduate / Post graduate students in Engineering / Biological / Chemical sciences/ Medical discipline.

Duration
October 24 – 26, 2013

Venue
Biotech Park,
Sector-G, Jankipuram,
Near Biotech Square,
Kursi Road, Lucknow-226021,
Uttar Pradesh, India.
E-mail: info@biotechpark.org.in, sna.biotechpark@gmail.com
biotechpark.org.in

SEATS ARE AVALABLE
Registration Fee
Rs 2,000/- per participant. The registration fee includes lectures/presentation handouts, stationary, lunch and tea. Fee is to be paid through bank draft drawn in favour of “CEO, Biotech Park, Lucknow”, Completed registration form along with the fee should reach to Biotech Park, Lucknow on or before October 21, 2013.

Faculty
The faculty will consist of scientists and teachers from local institutions who have wide experience in bioinformatics, Genomics & Proteomics, drug development and biotechnology.

Accommodation

Lucknow has different categories of Hotels. Person desiring Hotel accommodation are adviced to book their accommodation directly. For Guest House accommodation contact us by E-mail sna.biotechpark@gmail.com

FOR MORE DETAILS CLICK HERE TO DOWNLOAD BROCHURE AND REGISTRATION FORM

For any queries please contact with
Sunil Kumar Gupta
Convener, Bioinformatics Workshop,
Bioinformatics Center
Biotech Park
Lucknow (U.P.) India
Email: sna.biotechpark@gmail.com, skgupta@biotechpark.org.in

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