M.Pharm

Glenmark Pharmaceuticals today announced the settlement of litigation with Daiichi Sankyo and Genzyme Corporation regarding Glenmark's Abbreviated New Drug Application (ANDA) tiled with the US Food and Drug Administration (FDA) for Colesevelam Hydrochloride, a drug used in treatment of type-2 diabetes.

About Authors:
Amit A. Patel , Dr.Vipin Kukkar, Sanjeev Thacker
Seth G. L. Bihani S.D. College of Technical Education,
Institute of Pharmaceutical Sciences and Drug Research,
Sri Ganganagar, Rajasthan, INDIA.

ABSTRACT:
Food additives have been much important in food product manufacturing. Additive” became almost synonymous with “adulteration. Food additives are used in the food product toprovide nutrition,to maintain product quality and freshness, to look good. There are many type of food additives are available in the market like anti-oxidants, preservatives,Emulsifier and stabilizers,Sweetener, etc.The “E” number system, intended to assist as a short code for some of the lengthier chemical names and to indicate common European safety approval.

Indian Institute of Technology Roorkee, Roorkee invites the applications on the prescribed form for the following posts as per details given against each. The application form and general conditions may be obtained from Superintendent, Establishment ‘B’ Section, IIT Roorkee.

Established in the year 2000 as a Biocon subsidiary, Clinigene became India's first CAP (College of American Pathologists) accredited Central Laboratory.

MOLECULES INVOLVED IN REGULATION OF STEM CELL DIFFERENTITIATION
Cell adeshive molecule E_cadhedrin which replaces oct 4signalling molecule there by converting normal somatic cell into pluripotent

About Authors:
RAVISANKAR.M*¹, SUBASINI.U², ANAND THANGADHURAI.S³, KARTHIKEYAN.S⁴, CHANDRA SEKAR.E.^5
1.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode
^2.Swamy Vivekanandha College of pharmacy, dept of pharmacognosy. Thiruchengode
^3.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode
^4.Kausikh therapeutics and private limited.chennai
^5.Swamy Vivekanandha College of pharmacy, dept of pharmaceutical analysis. Thiruchengode

ABSTRACT
An isocratic reverse phase high performance liquid chromatographic method for estimation of montelukast sodium and levocetirizine in bulk dosage and in marketed formulations has been devised and validated. The chromatographic separation achieved on shodex c18-4E column (5µm, 250 mm x 4.6 mm) and  acetonitrile: methanol: ammonium acetate buffer (PH- 5.5) in the ratio of 25:55:20 v/v. The flow rate was 1.0 ml/min and the UV detection was identified at 225nm.The retention times for montelukast sodium and levocetirizine was found to be 5.15 min and 3.12 min respectively. The linearity of montelukast sodium and levocetirizine is 10 -50µg/ml with the correlation co efficient 0.99 respectively. The validation parameters such as accuracy, precision, LOD, LOQ, Robustness, ruggedness were performed as per ICH guidelines. This method can be used for routine analysis of montelukast sodium and levocetirizine in bulk and marketed dosage forms.

Recruitment applications are invited On-line through the proforma Application to be made available on WEBSITE (apspsc.gov.in) in from 22/02/2012 to 22/03/2012 (Note: 20/03/2012 is the last date for payment of fee) for recruitment to the post of Drug Inspector in A.P. Drugs Control Administration Service.

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