Chennai

8 November 2012

HBL invites Deputy Manager - Formulation, Production, QA, QC, Regulatory Affairs, Animal House

HLL Biotech Limited (HBL) is a 100% subsidiary of HLL Lifecare Limited, a Mini Ratna Schedule B Central Public Sector Enterprise under the Ministry of Health & Family Welfare. HBL is setting up a vaccine complex at Chengalpett, Chennai for manufacturing of Bacterial and Viral Vaccines & developing a strong R&D base for vaccine technologies within the country.

8 November 2012

Work as Area sales Executive/Medical representative in Synergy Diagnostics - Freshers may apply

Synergy Diagnostics pvt Ltd, a Leading Bio-pharmaceutical company, with the Largest range of human blood plasma derived bio-pharmaceutical products, used in the prophylaxis & treatment of various life-threatening conditions.We are basically in to Sales & Marketing of imported products Manufactured from Human Blood. Products manufactured are injectable & critical care products.

5 November 2012

PREPARATION OF VILOXAZINE SUSTAINED RELEASE DRUG DELIVERY SYSTEM BY USING ETHYLCELLULOSE, CARBOPOL, SODIUM ALGINATE, HYDROXY PROPYL METHYL CELLULOSE & GUAR GUM

About Authors:
D. HariHaran*, M. Senthil kumar, M. Ashok Kumar, S. Dinesh & R.Jenish.
Annai Veilankanni’s College of Pharmacy,
81, V.G.P. Salai, Saidapet, Chennai-600015.
*haran_pharma@yahoo.com

ABSTRACT
The present study behind this work is to find to prepare sustained release tablets of Viloxazine by compression method. First of all to formulate Viloxazine sustained release tablets using the Ethylcellulose, Carbopol, Sodium Alginate, Hydroxy propyl methyl cellulose & Guar gum under ratio’s like 1:1, 1:1, 1:1,1:1,1:1 . Five batches were made in various polymers of ethylcellulose, carbopol, sodium alginate,hydroxy propyl methyl cellulose & guar gum is used by keeping the drug as constant. Then evaluation of Viloxazine sustained release tablets was carried out for characteristics like drug content in tablet, UV analysis. In vitro release starts from 1hr and up to 24hrs. It shows the percentage of gradual drug release as 17.80%, 27.65%, 35.12%, 45.16%, 51.20%, 57.42%, 61.30%, 66.32%, 72.08%, 77.15%, 81.32%, 84.48% & 98.20% against the label claim as 40mg.

30 October 2012

“Professional Certificate in Pharmacovigilance” program by Catalyst Clinical Services | Special Discount of 10% for Pharmatutor Visitors

Pharmacovigilance is the pharmacological sciences relating to the detection, assessment, understanding and prevention of adverse effects, particularly long term and short term side effects of the therapeutic drugs, devices and biologics. Setting up of stringent laws by regulatory bodies (e.g.

29 October 2012

DEVELOPMENT AND VALIDATION OF QUETIAPINE BY HPTLC METHOD

About Author:
Gautam Kumar
SRM college of pharmacy,SRM University
Chennai 600 033.
gautamsinghsrmcp@gmail.com

Abstract
The aim of the present work is to develop validated HPTLC method which determines stress stability and concentration of Quetiapine and its formulation as per ICH guidelines. Separation was performed using Camag Linomat V semi Automated sample applicator with TLC Scanner III. HPTLC analytical measurement and separation were performed using Stationary Phase consisting of TLC plates (Merck) pre coated with silica gel 60F254 on Aluminum Sheets was used. Mobile phase comprising of Methanol: Toluene (7:3 v/v) was used. All the system suitability parameter was found within the range. Area under curve was measured at 235nm. The method was extensively validated for specificity, linearity, accuracy, precision, recovery, limit of quantitation and detection. The proposed method can be used for routine analysis of Quetiapine in quality control laboratories.

21 October 2012

FORMULATION AND INVITRO EVALUATION OF IMMEDIATE RELEASE FOR QUETIAPINE FUMARATE IN TABLET DOSAGE FORM

About Authors:
Ashokkumar.m*, M.Senthil kumar, Dinesh, Jenish, Marshel, Hariharan
Annai veilankanni’s college of pharmacy
Saidapet, Chennai-600015, Tamilnadu
*mgashokkumar123@gmail.com

ABSTRACT
Atypical antipsychotic Quetiapine was used for the treatment of schizophrenia is a severe illness with substantial effects on individual and social functioning, Quetiapine and its active metabolite N-desalkyl-Quetiapine have affinities to dopaminergic D1-and D2receptors,5-HT2 receptors. To design of immediate release dosage form of quetiapine fumarate that will help in releasing drug with short period of time. The quetiapine fumarate tablets were successfully prepared by direct compression method. The physiochemical evaluation results for the powdered material of all trials pass the official limits in angle of repose, compressibility index and drug content. In the 9 trials, the optimized formulation was F3 trial which releases the quetiapine fumarate immediately within an hour.

18 October 2012

Applications are invited for the post of studentship in Anna University - 2 Nos

16 October 2012

Find Jobs for M.Pharm, M.Sc, B.Pharm, B.Sc, MBBS, MD & More for month Jul 2012

Career as Drug Safety Associate @ Icon Clinical Research
science degree, pharmacy or nursing background you will have a minimum of 8 months experience in a drug safety environment.