The United States Pharmacopeia (USP) is a non–governmental, official public standards–setting authority for prescription and over–the–counter medicines and other healthcare products manufactured or sold in the United States. USP also sets widely recognized standards for food ingredients and dietary supplements. USP sets standards for the quality, purity, strength, and consistency of these products–critical to the public health. USP's standards are recognized and used in more than 130 countries around the globe. These standards have helped to ensure public health throughout the world for close to 200 years.
Post: Scientist - III, Synthetic Laboratory
Function of the Position:
This is a non-supervisory position responsible for route synthetic route development, validation, preparation, isolation and purification of a variety of impurities and chemical compounds for drugs.
Roles and Responsibilities:
Responsible for carrying out literature search to arrive at various synthetic pathways of the organic compounds of interest by which a candidate material can be synthesized.
Good knowledge of synthetic organic chemistry, able to propose new routes of synthesis, able to make suitable modifications in existing routes to make it cost effective and eco-friendly.
Responsible in synthesis of organic compounds by various routes of synthesis and name reactions, product identification and purification through various techniques.
Thorough in trouble shooting, able to analyze the problem encountered during the reaction and able to make suitable modification to solve the problem
Conversant with lab safety norms
Responsible for performing R&D of the synthetic schemes and validate the rout of synthesis
General Material balance, Process Flow Diagrams (PFD), Recovery of solvents, Selection of equipments etc.,
Characterization of compounds based on IR, NMR, Mass Spectra, Elemental analysis etc.
To execute and completes the projects as per the time lines.
Ensuring that the Chemicals, equipments and glass wares etc are available for the projects and forward the purchase requisitions.
Periodic check of the assigned equipments to ensure that equipment is in good condition.
To follow QMS systems of USP
Responsible for preparation and review of SOPs, Protocols, reports etc.
Responsible for review the records and documents
Responsible to ensure the calibrations of the equipments are as per the schedule
Responsible for preparing, executing and completing IQ/OQ/PQ of new instruments
Knowledge, Skills, Abilities, Training and Experience:
Knowledge of GMP/GLP/ISO laboratory requirements. Familiar with a variety of synthetic chemistry principles, theories and practices, including separation science. Able to perform chemistry literature search using different soft wares. Able to carry out multiple small scales reactions at a time and validate the route of synthesis. Able to carry out different types of chemistries. Excellent written and oral scientific communication skills. Exposure to various routes of synthesis and characterization techniques such as NMR, IR, Mass Spectra, XRD, DSC, and other analytical interpretations through HPLC, GC, FTIR, UV-Visible etc is desirable. Familiarity with ISO guidance on Reference Materials and an understanding of associated statistics and metrological principles.
For More Info Go to Next Page...
Reference Standards Development and Testing Laboratory
M.Sc in Synthetic organic chemistry with about 5-7 years R&D experience in medicinal chemistry. A strong background in synthetic organic chemistry. Ph.D with 2-3 years of R&D experience in medicinal chemistry can also be considered. Should have exposure to GMP/GLP environment and documentation procedures. Have good Practical, Communication & Presentation Skills. Hands on experience in total synthesis of Specialty Chemicals, Contact Research Projects, API’s and Drugs products etc. Familiar with General Material balance, Process Flow Diagrams (PFD), Recovery of solvents, Selection of equipments, etc
Experience: 2-3 Years
Education: M.Sc, Ph.D
Industry Type: Pharma/ Healthcare/ Clinical research
Functional Area: R&D
End Date: 30th Aug., 2013
See All Other Jobs in our Database