A STUDY ON ANTIULCER ACTIVITY OF ACACIA LEAUCOPHLOEA BARK EXTRACT IN PYLORUS LIGATED RATS
About Authors:
Kapil Patel, Supriya Hazra Das
Department of Pharmacology
Shree Dhanvantary Pharmacy College,
Kim, Surat – 394118,
Gujarat, India
Abstract:
Peptic ulcer is a condition where benign lesions of gastric or duodenal mucosa occur at a site where the mucosal epithelium is exposed to acid and pepsin, due to imbalance between offensive and defensive factors. Acacia leucophloea, a deciduous tree found throughout India is reported to be used in gastric ulcer in traditional medicine. The present study was undertaken to evaluate the anti-ulcer properties of Acacia leucophloea in pylorus ligation ulcer model in rats. Acacia leucophloea was administered for 7 days and on 8th day 30 min prior to the induction of ulcers. Pretreatment with Acacia leaucophloea showed significant ulcer protection against pylorus ligation ulcer model as compared to control. Thus, the ulcer protective and healing effects of Acacia leucophloea may be due to its effect on both offensive and defensive factors. The present findings suggest that Acacia leucophloea has antiulcer properties.

About Authors:
About Authors:
The University
The Government of India, through the Ministry of Human Resource Development (MHRD), and based on the recommendation of Scientific Advisory Council to the Prime Minister, decided to create five undergraduate science universities. One of them is located at Kolkata and was started from 2006.
About Authors:
AXA Parenterals Ltd is into manufacturing & marketing of Sterile Parenteral preparations, life saving medicines and hospital products.
