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PharmaTutor (November- 2013)


Received On: 08/10/2013; Accepted On: 02/11/2013; Published On: 25/11/2013


Amardeep Sharma
Rathi Orthopaedic & Research Centre,
Ahmedabad, Gujarat, India


ABSTRACT: The knowledge of breast cancer development and progression has grown in recent years and relatively development of novel therapeutic strategies, but for cancer mortalities in women breast cancer stands at 2nd position as cause.

In U.S. Approximately 39970 women & 450 men in the U.S. will be diagnosed from the disease in 2011. Breast cancer is a hormone dependent disease. Breast cancer occurs when breast epithelial cells grows in abnormal way. HER2/neu, ER, PR, BRCA1, BRCA2 are the well known influencing factors responsible for breast cancer initiation. The major issues that limit the currently available breast cancer treatment are high cost, poor availability and resistance to chemotherapeutic agents. To overcome this problem researchers are working on several novel approaches i.e. “Novel drug targets & Novel target therapies”.

Since from past few years, mammogram is playing a huge role for decreasing incidence rate in developed countries. Breast cancer is adversely affecting the “quality of life” of patients and its impact has been increasing on the Social capital, population structure and economic growth. Need for novel anti breast cancer agent and novel early diagnosis technique is necessary to combat one of the most serious crises facing Human development.


How to cite this article: Sharma A, Breast Cancer: An Overview, PharmaTutor, 2013, 1(1), 29-38