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A Review on Chalcones Synthesis and their Biological Activity


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February 2018 ARTICLE LIST >>

PharmaTutor (February - 2018)


ISSN: 2347 - 7881
(Volume 6, Issue 2)


Received On: 22/12/2017; Accepted On: 22/12/2017; Published On: 01/02/2018


Shipra Verma1, Alok Kumar Srivastava*1, O.P. Pandey2
1Department of Chemistry,
Mahatma Gandhi P. G. College, Gorakhpur, U. P., India
2Department of Chemistry,
D.D.U. Gorakhpur University, Gorakhpur, U.P., India



Chalcones are a valuable molecule of medicinal importance due to presence of reactive ketoethylenic group –CO–CH=CH–, belonging to the flavonoid family. These reactive α,β-unsatutated keto function in chalcones are  responsible for their biological activity. Chalcone can be synthesized by several methods using aldehydes and ketones as starting material. This review is focused about different methods of synthesis and versatile biological activity of chalcones including antimicrobial, anticancer, antioxidant, antimalarial, antituberculosis etc.



How to cite this article: Verma S, Srivastava AK, Pandey OP; A Review on Chalcones Synthesis and their Biological Activity; PharmaTutor; 2018; 6(2); 22-39;