A Review on Immediate Release Drug Delivery Systems
PharmaTutor (August- 2014)
ISSN: 2347 - 7881
(Volume 2, Issue 8)
Received On: 10/06/2014; Accepted On: 16/06/2014; Published On: 01/08/2014
AUTHORS: Mohalkar Rahul1*, Poul Bhagwat2, Patil S.S1, Shetkar M.A1, Dilip Chavan1
1Department of Quality Assurance, Maharashtra College of Pharmacy, Nilanga, India.
2Principal of Maharashtra College of Pharmacy, Nilanga,
Latur, Maharashtra, India.
The oral drug delivery system which includes the solid dosages form such as conventional dosages form and immediate release dosages form. Form last several decades conventional dosage forms like capsule, solid, pills, powder, solution, emulsion, suspension aerosols are used in the various treatments of acute or chronic disease. Today this formulation can be considered as primary pharmaceutical product are mostly seen in overalls market. Tablet is most popular among the all dosages forms today and recently found mostly accepted tablet dosages forms. Because of its convenience easy to administration, convenience of self administration, compactness and easy for the manufacturing. In number of cases immediate onset of action is required than conventional therapy. The basic approach used in development immediate release solid dosages form by using superdisintegrant like sodium starch glycolate (Primogel, Explotab), Polyvinylpyrrolidone (PVP) etc. which provides in instantaneous disintegration of tablet after administration. By using various techniques in can be formulate like wet granulation, direct compression etc. Hence its having A new dosage form allows a manufacturer to extend market exclusivity, while offering its patient population a more convenient dosage form or dosing regimen.
While development if immediate release therapy also provides an opportunity for a line extension in the marketplace, wide range this dosage form. As a drug entity nears the end of its patent life, it is common for pharmaceuticals manufacturer to extend to development a given drug entity in a new and improved dosage form. A new dosage form slows a manufacturer to extend market exclusivity, white offering its patient population a more convenient dosages form or dosing regimen.
Pharmaceutical products designed for oral delivery and currently available on the prescription and over-the-counter markets are mostly the immediate release type, which are designed for immediate release of drug for rapid absorption.
Tablets were prepared by wet granulation method using fast releasing excipients such as and superdisintegrant sodium starch glycolate (SSG).
How to cite this article: R Mohalkar, B Poul, SS Patil, MA Shetkar, D Chavan; A Review on Immediate Release Drug Delivery Systems; PharmaTutor; 2014; 2(8); 95-109