Oral Controlled Release Drug Delivery System- A Review

  • Posted on: 1 August 2014
  • By: admin

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PharmaTutor (August- 2014)
ISSN: 2347 - 7881
(Volume 2, Issue 8)


Received On: 29/05/2014; Accepted On: 03/06/2014; Published On: 01/08/2014


AUTHORS: Manisha Gahlyan*, Saroj Jain
Department of Pharmaceutics,
Hindu college of pharmacy
Near Panchayat Bhawan, Gohana Road, Sonepat, Haryana


Oral route has been the most popular and successfully route for controlled delivery of drugs because of the flexibility in the designing of dosage form than other routes. The immidiate release conventional dosage form lack in the efficiency of controlling the proper plasma drug concentration. This factor as well as factors such as repetitive dosing ++ and unpredictable absorption leads to the concept of oral controlled release drug delivery systems. A desirable characteristic of controlled release delivery system is that the duration of drug action should be dictated by the design property of drug molecules. There are different mechanistic aspects for design of oral controlled release drug delivery systems such as matrix, reservoir, osmotic pressure, ion exchange resins, altered density etc. This article contains brief review on currently existing oral controlled system and various formulation approaches for the controlled release system.


How to cite this article: M Gahlyan, S Jain; Oral Controlled Release Drug Delivery System- A Review; PharmaTutor; 2014; 2(8); 170-178