Board Advertisement No.: 415/202627, Junior Pharmacist, Class-3 Cadre Published Advertisement
Important Notice Regarding Competitive Test Date
Gujarat Subordinate Services Selection Board has decided to organize the examination through MCQ CBRT method for the advertisement mentioned in the sheet below under direct recruitment.
Notifications regarding the call-letter of MCQ - CBRT examination will be published on the Board's website later.
Advertisement No./Cadre Name : 415/202627, Junior Pharmacist, Class-3
Name of Department/Head of Department : Health and Family Welfare Department/Additional Director Medical Services
Examination Date : 30/08/2026, Sunday
Examination Time : 15:30 to 18:30 hrs
If for any reason there is a need to change or cancel the examination schedule, the Board shall have the full right/authority to do so and the Board shall not be bound to give reasons for this, which the concerned candidates are requested to take note of.
DETAILED SYLLABUS OF EXAM
PART : A (90 MARKS)
(1) Reasoning & Data Interpretation (30 Questions, 30 Marks)
1. Problems on Ages
2. Venn Diagram
3. Visual reasoning
4. Blood Relation
5. Arithmetic Reasoning
6. Data interpretation (charts, graphs, tables)
7. Data Sufficiency
(2) Quantitative Aptitude (30 Questions, 30 Marks)
1. Number Systems
2. Simplification and Algebra
3. Arithmetic and Geometric Progression
4. Average
5. Percentage
6. Profit-Loss
7. Ratio and Proportion
8. Partnership
9. Time and Work
10. Time, Speed and Distance
11. Work, Wages and Chain Rule
(3) Constitution of India (10 Questions, 10 Marks)
1. Preamble of the Constitution
2. Fundamental Rights
3. Directive Principles of State Policy
4. Fundamental Duty
5. Power, Role and Responsibility of President, Vice President and Governor
6. Parliamentary System
7. Amendment of Indian Constitution, Emergency Provisions in Indian Constitution
8. Centre – State Government and Their Relation
9. Judicial System of Indian Constitution
10. Constitutional Bodies
(4) Current Affairs (10 Questions, 10 Marks)
1. Current Events of State, National and International Importance
(5) Comprehension (Gujarati {5 marks} & English {5 marks}) (10 Questions, 10 Marks)
1. To Assess Comprehension, Interpretation and Inference Skills A paragraph given with set of question on the basis of paragraph or statement and assertion type question can be asked.
PART : B (120 MARKS)
(4) Questions and Its Applications related to Educational Qualification (120 Questions, 120 Marks)
PHARMACOLOGY - 15 MARKS
General Pharmacology. Introduction to Pharmacology. Pharmacokinetics. Pharmacodynamics, Adverse drug reactions, Drug interactions, Drug discovery and clinical evaluation of new drugs. Pharmacology of drugs acting on peripheral nervous system, Pharmacology of drugs acting on central nervous system. Pharmacology of drugs acting on cardio vascular system, Pharmacology of drugs acting on urinary system, Autacoids and related drugs, Pharmacology of drugs acting on endocrine system, Bioassay. Pharmacology of drugs acting on Respiratory system, Pharmacology of drugs acting on the Gastrointestinal Tract, Chemotherapy. Immunopharmacology, Principles of toxicology. Chronopharmacology.
HUMAN ANATOMY AND PHYSIOLOGY 10 Marks
Introduction to human body, Cellular level of organization, Tissue level of organization, Integumentary system, Skeletal system, Joints, Body fluids and blood, Lymphatic system, Peripheral nervous system, Special senses, Cardiovascular system, Nervous system, Digestive system, Energetics, Respiratory system, Urinary system, Endocrine system, Reproductive system, Introduction to genetics.
PHARMACEUTICS 10 Marks
Historical background and development of profession of pharmacy. Dosage forms, Prescription, Posology, Pharmaceutical calculations, Powders, Liquid dosage forms, Monophasic liquids, Biphasic liquids, Suspensions, Emulsions, Suppositories, Pharmaceutical incompatibilities, Semisolid dosage forms.
PHARMACEUTICAL INORGANIC CHEMISTRY 05 Marks
Impurities in pharmaceutical substances; Acids, Bases and Buffers; Major extra and intracellular electrolytes, Dental products, Gastrointestinal agents, Miscellaneous compounds, Radiopharmaceuticals.
PHARMACEUTICAL ORGANIC CHEMISTRY 05 Marks
Classification nomenclature and isomerism; Alkanes, Alkenes and Conjugated dienes; Alkyl halides, Alcohols, Carbonyl compounds, Carboxylic acids, Aliphatic amines, Benzene and its derivatives, Phenols, Aromatic Amines, Aromatic Acids, Fats and Oils, Polynuclear hydrocarbons, Cyclo alkanes, Stereo isomerism, Optical isomerism, Geometrical isomerism, Heterocyclic compounds.
BIOCHEMISTRY 10 Marks
Biomolecules, Bioenergetics, Carbohydrate metabolism, Biological oxidation, Lipid metabolism, Amino acid metabolism, Nucleic acid metabolism and genetic information transfer, Enzymes.
PATHOPHYSIOLOGY 10 Marks
Basic principles of Cell injury and Adaptation, Basic mechanism involved in the process of inflammation and repair, Cardiovascular System, Respiratory system, Renal system, Haematological Diseases, Endocrine system, Nervous system, Gastrointestinal system, inflammatory bowel diseases, jaundice, hepatitis (A,B,C,D,E,F) alcoholic liver disease, Disease of bones and joints, Principles of cancer, Diseases of bones and joints, Principles of Cancer, Infectious diseases, Sexually transmitted diseases.
PHYSICAL PHARMACEUTICS 10 Marks
Solubility of drugs, States of Matter and properties of matter, Physicochemical properties of drug molecules, Surface and interfacial phenomenon, Complexation and protein binding, pH, buffers and Isotonic solutions, Colloidal dispersions, Rheology. Deformation of solids, Coarse dispersion, Micromeretics, Drug stability.
PHARMACEUTICAL MICROBIOLOGY 05 Marks
Introduction, history of microbiology, its branches, scope and its importance, Introduction to Prokaryotes and Eukaryotes, Study of ultra-structure and morphological classification of bacteria, nutritional requirements, raw materials used for culture media and physical parameters for growth, growth curve, isolation and preservation methods for pure cultures, cultivation of anaerobes, quantitative measurement of bacterial growth (total & viable count). Study of different types of phase contrast microscopy, dark field microscopy and electron microscopy. Identification of bacteria using staining techniques (simple, Gram's & Acid fast staining) and biochemical tests (IMVIC), Study of principle, procedure, merits, demerits and applications of physical, chemical gaseous, radiation and mechanical method of sterilization. Evaluation of the efficiency of sterilization methods. Equipments employed in large scale sterilization. Sterility indicators.Study of morphology, classification, reproduction/replication and cultivation of Fungi and Viruses. Classification and mode of action of disinfectants, Factors influencing disinfection, antiseptics and their evaluation. For bacteriostatic and bactericidal actions, Evaluation of bactericidal & Bacteriostatic Sterility testing of products (solids, liquids, ophthalmic and other sterile products) according to IP, BP and USP. Designing of aseptic area, laminar flow equipments, study of different sources of contamination in an aseptic area and methods of prevention, clean area classification. Principles and methods of different microbiological assay. Methods for standardization of antibiotics, vitamins and amino acids. Assessment of a new antibiotic, Types of spoilage, factors affecting the microbial spoilage of pharmaceutical products, sources and types of microbial contaminants, assessment of microbial contamination and spoilage. Preservation of pharmaceutical products using antimicrobial agents, evaluation of microbial stability of formulations Growth of animal cells in culture, general procedure for cell culture, Primary, established and transformed cell cultures. Application of cell cultures in pharmaceutical industry and research.
MEDICINAL CHEMISTRY 10 Marks
Introduction to Medicinal Chemistry, History and development of medicinal chemistry. Physicochemical properties in relation to biological action, Drug metabolism, Drugs acting Autonomic Nervous System, Adrenergic on Neurotransmitters, Sympathomimetic agents: SAR of Sympathomimetic agents, Adrenergic Antagonists, Cholinergic neurotransmitters, Parasympathomimetic agents: SAR of Parasympathomimetic agents, Direct acting agents, indirect acting/Cholinesterase inhibitors (Reversible & Irreversible), Cholinesterase reactivator, Cholinergic Blocking agents, Solanaceous alkaloids and analogues, Synthetic cholinergic blocking agents. Drugs acting on Central Nervous System, Antihistaminic agents, HI- antagonists, H2-antagonists, Gastric Proton pump inhibitors, Anti-neoplastic agents, Alkylating agents, Antimetabolites, Antibiotics, Plant products, Anti- anginal, Vasodilators, Calcium channel blockers, Diuretics, Anti- hypertensive Agents. Anti-arrhythmic Drugs, Anti-Hyperlipidemic agents, Coagulant & Anticoagulants. Drugs used in Congestive Heart Failure, Drugs acting on Endocrine system, Sex hormones. Drugs for erectile dysfunction, Oral contraceptives, Corticosteroids. Thyroid and Anti-Thyroid drugs, Anti- Diabetic agents. Local Anesthetics. Benzoic Acid derivatives, Amino Benzoic acid derivatives, Lidocaine/Anilide derivatives, Antibiotics, B- Lactam antibiotics, Aminoglycosides, Tetracyclines, Macrolide, Prodrugs. Anti-Malarials, Quinolines, Biguanides and dihydro triazines, Anti- Tubercular Agents, Synthetic sati Tubercular agents, Anti Tubercular antibiotics, Urinary tract anti-Infective agents, Antiviral agents Antifungal agents, Antifungal antibiotics, Synthetic Antifungal agents, Anti-Protezoal Agents Antheiminties, Sulphonamides and Sulfones, Folate reductase inhibitors, Introduction to Drug Design. Combinatorial Chemistry,
PHARMACOGNOSY AND PHYTOCHEMISTRY 10 Marks
Introduction to Pharmacognosy, Classification of drugs, Quality control of Drugs of Natural Origin Cultivation, Collection, Processing and storage of drugs of natural origin, Conservation of medicinal plants, Plant tissue culture, Pharmacognosy in various systems of medicine, Introduction to secondary metabolites, Plant Products, Primary metabolites, Carbohydrates, Proteins and Enzymes, Lipids(Waxes, fats, fixed oils), Marine Drugs, Metabolic pathways in higher plants and their determination, Alkaloids, Phenylpropanoids and Flavonoids, Steroids, Cardiac Glycosides & Triterpenoids, Volatile oils, Tannins, Resins, Glycosides, Iridoids, Other terpenoids & Naphthoquinones, Isolation, Identification and Analysis of Phytoconstituents, Basics of Phytochemistry
PHARMACEUTICAL JURISPRUDENCE : 10 Marks
(A)Drugs and Cosmetics Act, 1940 and its rules 1945 (B)Pharmacy Act-1948 (C)Narcotic Drugs and psychotropic substances Act-1985 and Rules (D)Study of Salient Features of Drugs and Magic Remedies Act and its rules (E)Prevention of Cruelty to animals Act-1960 (F)National Pharmaceutical Pricing Authority (G) Code of Pharmaceutical ethics (H)Right to Information Act, 2005 (I)Introduction to intellectual Property Rights (IPR)
Current Trends and Recent Advancements in the Above Fields. 10 Marks
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