• PharmaTutor
    5 July 2013

    HERBAL REMEDIES USED IN THE TREATMENT OF EPILEPSY

    ABOUT AUTHORS:
    Sachchidanand Pathak*, L Singh, T Singh, S K Sharma
    Sunder Deep Pharmacy College,
    Ghaziabad, Uttar Pradesh, India
    sachchidanand.pathak904@gmail.com

    ABSTRACT- 
    This article has been made to review of following plants used for the antiepileptic activity. The plant sources of India are likely to provide effective antiepileptic agents. Herbs have a vital role in the prevention and treatment of convulsion. The phytochemical exploration of these herbs has contributed to some extent in this race for the discovery of new antiepileptic drugs (AED). In recent years owing to the fear of side effects people prefer more and more use of natural plant products for convulsions. This review also helps to summarize the diverse methodologies and ways to evaluate the potential natural compounds having antiepileptic activity.

    Convulsion is the second most common neurologic disorder after stroke. Approximately 1% of the world’s population has convulsion, it is a condition where the patient suffers from recurrent seizures. Control to seizures numerous conventional drugs came into existence. Most of the epileptic patients need polytherapy of conventional anticonvulsants and still not 100% cured.

    The major drawback due to these agents is their chronic side effects and drug interactions which restrict its use. On the other hand nature has provided us plants to be used as natural remedy for diseases with least side effects and insignificant drug interactions. This has motivated the researchers towards herbal remedy for anticonvulsant activity. In this review, herbal drugs have been discussed with more emphasis on the research advancements of traditional or herbal anticonvulsants.

  • REMOTE INTELLIGENT DRUG DELIVERY SYSTEM: A POTENTIAL DEMAND
    4 July 2013
    REMOTE INTELLIGENT DRUG DELIVERY SYSTEM: A POTENTIAL DEMAND

    ABOUT AUTHORS:
    Nitish Maini*, Saroj Jain, Satish Sardana
    Hindu College of Pharmacy,
    Sonipat, Haryana, India
    *nitishmaini@yahoo.com

    ABSTRACT
    Patients who may otherwise be unable to take medication may benefit from new electronic implants capable of dispensing drugs automatically. The Remote Intelligent Drug Delivery System (RIDDS), a device implanted under the skin and connected to a wireless control center, overcomes the inconvenience associated with taking drugs manually. Such devices include built-in sensors that allow health care workers to monitor pulse rate, blood oxygen levels and other functions. Based on the information, they can adjust how frequently the medication is delivered or increase or decrease amounts as necessary. Nowadays, the Remote Intelligent Drug Delivery System (RIDDS) is a potential demand as they will be especially beneficial for people with physical or mental disabilities, who would otherwise be unable to take medications on their own.

  • A REVIEW ARTICLE ON SYNRIAM INDIAs FIRST ANTI-MALARIAL DRUG
    4 July 2013
    A REVIEW ARTICLE ON SYNRIAM INDIAs FIRST ANTI-MALARIAL DRUG

    ABOUT AUTHOR:
    Shikha Patel
    M.pharm (Quality Assurance), Sagar Institute of Research and Technology-Pharmacy
    Bhopal (M.P)
    siyapatel2007@gmail.com

  • REVIEW: REGULATORY PROVISIONS REGARDING COSMETICS IN INDIA
    3 July 2013
    REVIEW: REGULATORY PROVISIONS REGARDING COSMETICS IN INDIA

    ABOUT AUTHOR:
    Abhijeet Welankiwar
    Govt. college of Pharmacy,
    kathora naka,
    Amravati (Maharashtra), 444604.
    abhi123welankiwar@gmail.com

    ABSTRACT:
    The Government of India through the Drug and Cosmetic act 1940 and rules 1945 has made stringent provisions regarding import, Manufacturing, Sale and Distribution of Cosmetics. These provisions mainly cover the licensing for the import, manufacturing of cosmetics and also the GMPs for the manufacturing of cosmetics. Also these guidelines have covered certain categories of cosmetics whose import and sale is prohibited by the Law. These guidelines have also listed the 28 cosmetics whose import is allowed only on to the conformance to the Indian standards. These guidelines have also covered the offences and penalties in case of contravention of the provisions of the Drug and Cosmetic Act 1940.

  • ANALYTICAL METHOD DEVELOPMENT & VALIDATION FOR ESTIMATION OF TERAZOSIN HYDROCHLORIDE EQUIVALENT TO TERAZOSIN IN TABLET DOSAGE FORM
    3 July 2013
    ANALYTICAL METHOD DEVELOPMENT & VALIDATION FOR ESTIMATION OF TERAZOSIN HYDROCHLORIDE EQUIVALENT TO TERAZOSIN IN TABLET DOSAGE FORM

    ABOUT AUTHORS:
    Ritobrata Rudra*1, Sudipta Ganguly2, Manabendra Dhua3, Binny sikdar4
    1Department of pharmaceutical chemistry, Gupta College of Technological Sciences, Asansol.
    2Department of Quality control, Stadmed pharmaceutical pvt ltd, Dumdum, Kolkata.

  • DEVELOPMENT AND VALIDATION OF BIOANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF ETAMSYLATE AND MEFENAMIC ACID IN HUMAN PLASMA BY RP-HPLC METHOD
    2 July 2013
    DEVELOPMENT AND VALIDATION OF BIOANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF ETAMSYLATE AND MEFENAMIC ACID IN HUMAN PLASMA BY RP-HPLC METHOD

    About Authors:
    Mona Karia*1, Bhargav Gohel2, Bina Thanki3, Darshan Madiya4, Shital Faldu5
    1,3M.Pharm, Smt. R.D.Gardi B.Pharmacy College. Rajkot, Gujarat, India
    2Q.A. Officer, Intas Pharmaceutical Ltd., Ahemdabad.
    4Assistant Professor of Smt. R.D.Gardi B.Pharmacy College, Rajkot

  • DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF CEFIXIME TRIHYDRATE AND LEVOFLOXACIN HEMIHYDRATE IN TABLET FORMULATION
    2 July 2013
    DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF CEFIXIME TRIHYDRATE AND LEVOFLOXACIN HEMIHYDRATE IN TABLET FORMULATION

    ABOUT AUTHORS:
    Sejal K. Patel, Sumeet I. Chhabra*
    Department of Pharmaceutical Analysis,
    Centre For Health Science Studies, Ganpat University,
    Ganpat Vidyanagar – 384012, Mehsana, Gujarat, India
    *rxsumeet@gmail.com

  • THERMAL ANALYSIS: A USEFUL TOOL IN PREFORMULATION STUDY
    1 July 2013
    THERMAL ANALYSIS: A USEFUL TOOL IN PREFORMULATION STUDY

    About Author:
    Vivek P. Chavda
    Department of Pharmaceutics,
    B.K. Mody Government Pharmacy College,
    Rajkot – 360003, Gujarat (India)
    vivek7chavda@gmail.com

    Introduction
    Thermal method of analysis are group of techniques in which changes in physical and /or chemical properties of a substance are measured as a function of temperature, while substance is subjected to controlled temperature programmes.[1]Thermal analysis and calorimetric methods have demonstrated a wide array of applications in the Preformulation, and formulation development. These techniques are critical in physical–chemical screening of early discovery leads, during salt form screening, and in the characterization of polymorphs to determine the thermodynamic relationships between the various crystal forms.[2]

  • PHARMACEUTICAL GELS: IN SUMMARIZED FORM
    1 July 2013
    PHARMACEUTICAL GELS: IN SUMMARIZED FORM

    About Author:
    Piyush Tripathi
    Kota College of Pharmacy,
    Kota (RAJ)
    piyushtripathi1992@rediffmail.com

     

    Definition:
    A gel is a solid or semisolid system of at least two constituents, consisting of a condensed mass enclosing and interpenetrated by a liquid4.

  • DRIED BLOOD SPOT SAMPLING TECHNIQUE IN QUANTITATIVE ANALYSIS OF SMALL MOLECULES- A REVIEW
    30 June 2013
    DRIED BLOOD SPOT SAMPLING TECHNIQUE IN QUANTITATIVE ANALYSIS OF SMALL MOLECULES- A REVIEW

    ABOUT AUTHORS:
    Bhimavarapu Ramya Reddy*1, Bhavna Priyasri S2
    *1Department of Pharmaceutical Analysis, A.M Reddy Memorial College of Pharmacy, Narasaraopet, Guntur, Andhra Pradesh, India
    2Department of Pharmaceutical Engineering, New Jersey Institute of Technology, New Jersey, U.S.A.
    ramyareddy.bh@gmail.com

    ABSTRACT:
    Dried blood spots (DBS) as an attractive alternative to conventional venous plasma sampling in many pharmaceutical companies and clinical laboratories, different analytical approaches have been developed to enable automated handling of DBS samples without any pretreatment. DBS offers a number of advantages over conventional blood collection. As a less invasive sampling method, DBS offers simpler sample collection and storage and easier transfer, with reduced infection risk of various pathogens, and requires a smaller blood volume. DBS-LC-MS/MS has emerged as an important method for quantitative analysis of small molecules. This technique is Widely used to screen for metabolic problems in newborn babies, PK studies. The objective of this review is to describe the analytical concepts of current direct DBS techniques along with DBS sample collection, processing and storage and to present their advantages and disadvantages.

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