• PharmaTutor
    6 October 2013

    FORMULATION AND CHARACTERIZATION OF RALOXIFENE BETA-CYCLODEXTRINE INCLUSION COMPLEX FOR SOLUBILITY ENHANCEMENT

    ABOUT AUTHORS:
    Gazi Juned M.*1, Javia A.R1, Sheth A.K1, Sachinkumar P. Chauhan, Nirmal Shah
    1Department of Pharmacy, Sumandeep Vidyapeeth University,
    At & Po Pipariya, Ta.- Waghodia, Dist. Vadodara-391760.
    (Gujarat) India
    gaziriju89@gmail.com

  • 4 October 2013
    DEVELOPMENT AND VALIDATION OF IR SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF AZELASTINE HYDROCHLORIDE IN NASAL SPRAY PREPARATIONS

    ABOUT AUTHORS:
    *1Patel Rina B., 2Patel Nilam K.
    1M.pharm(Q.A), Department of Pharmaceutical Sciences
    Hemchandracharya North Gujarat University,
    2Asst. Professor, Dept. of Pharmaceutical Sciences
    Department of Pharmaceutical Sciences, Hemchandracharya North Gujarat University, Patan. Gujarat-384265
    *rina_patel2003@yahoo.com

    ABSTRACT
    A simple, sensitive, rapid, accurate, precise and economical Fourier transform infrared (FTIR) spectrophotometric method has been developed for the determination of Azelastine Hydrochloride (AZH)   in nasal spray preparations. The IR spectrophotometric method was based on the determination of AZH by the measurement of the area of the infrared band corresponding to the carbonyl group centred at the band1636 cm-1. It was present in the AZH but not in Acetonitrile used as solvent and highest intensity was at the area 1701.08-1584.21 cm-1. The linearity of AZH was obtained in the concentration range of 5-100 μg/ml. The mean % recovery was 99.67 ± 0.57 %. The recovery studies confirmed accuracy of proposed method and low values of standard deviation confirmed precision of method.

  • 4 October 2013
    A VISIT ON PHARMACEUTICAL INDUSTRIAL ORIENTATION

    About Authors:
    Dr. D.k. Sanghi, Rakesh Tiwle*, Puja Karanjekar, Priyanka Hemne, Dileshwari Madavi, Padma Tembhre
    Shri Laxmanrao Mankar Institute of Pharmacy,
    Amgoan, Gondia, Maharashtra, India- 441902.
    rakesh_tiwle@rediffmail.com

  • 3 October 2013
    BRAIN DRUG DELIVERY OF NANOPARTICLES BY NASAL ROUTE FOR THE TREATMENT OF DEPRESSION

    ABOUT AUTHORS:
    Rakhi Choudhary*, Lakshmi Goswami , Preeti Kothiyal
    Shri Guru Ram Rai Institute of Technology & Science P.O. Box - 80, Patel Nagar,
    Dehradun 248001, Uttarakhand , India
    rakhichaudhary211@gmail.com

  • 2 October 2013
    OVERVIEW: LYME DISEASE

    About Author:
    P. Bharath
    Department of pharmacology
    Teegala Ram Reddy College of Pharmacy
    Hyderabad (AP), 500097.
    pbharath760@gmail.com

  • 2 October 2013
    FORMULATION AND DEVELOPMENT OF VENLAFAXINE HYDROCHLORIDE EXTENDED RELEASE TABLET USING COMPRESSION COATING TECHNIQUE

    About Authors:
    K.Venkatakrishna
    Department of Pharmaceutics; Koringa college of pharmacy,
    Korangi (Andhra Pradesh) India.
    venky5019@gmail.com

    Abstract:
    Venlafaxine HCl is an anti depressent drug which is used in depreesion. It is available both as immediate release tablet as well as modified release product. The innovator modified release product available in international market is Effexor ER tablets. Effexor ER is based on erosion matrix system. The core tablet is coated with Ethyl Cellulose using PVP as a core former. This coating is solvent based coating. The aim of  present investigation was to prepare a ER tablet of Venlafaxine HCl  with similar dissolution profile matching to  Effexor ER  using  swelling  matrix system. The platform developed for this product was compression coating.  An immediate release  core tablet of 100mg  was prepared and it was compression coated using HPMC  matrix system. HPMC of three viscosity grades was selected and the concentration and the   viscosity grade were optimised. Similarity factor ( F2 values) with innovator product were calculated for in vitro dissolution profile.  The  rank order correlation for similarity factor was as under HPMC K15M 15% > HPMC K100M 15% > HPMC k15M 35% > HPMC k100M 35% > HPMCK 4M 15% > HPMC k45 45%. In this review, current and recent developments of venlafaxine hydrochloride extended release products are discussed.

  • 1 October 2013
    ANDROPAUSE-MALE MENOPAUSE

    ABOUT AUTHOR:
    Akshay Rajgaria
    Kanak Manjari Institute of Pharmaceutical Sciences
    Rourkela, Orissa
    akshaykrish2007@gmail.com

  • 1 October 2013
    PRENATAL NUTRITION; NUTRIENT RECOMMENDATIONS BEFORE, DURING & AFTER PREGNANCY

    About Authors:
    *Govind shukla1, Ms.Shivani prashar2, Ms. M.sarika3, Dr. Sunil Yadav4
    1M.Pharm(Ph.D), Product Manager
    2Sr. Product Executive, Shrey Nutraceuticals Pvt. Ltd. NewDelhi
    3Product Analyst, Lactonova India Hyderabad
    4Medical officer-in–charge, BPHC Bamore JHANSI  U.P.
    *govindbbd@gmail.com

    Abstract
    Nutrition before and during pregnancy has a profound effect on the development of infants. This is a rather critical time for healthy fetal development as infants rely heavily on maternal stores and nutrient for optimal growth and health outcome later in life. Prenatal nutrition addresses nutrient recommendations before and during pregnancy. Birth weight of the newborn at delivery reflects the sufficiency and the quality of maternal nutrient for the fetus during pregnancy. Prenatal nutrition has a strong influence on birth weight and further development of the infant.The present paper reviews the role of  prenatal nutrition in pregnancy.

  • 30 September 2013
    NEED FOR EFFICACY, SAFETY, QUALITY CONTROL AND REGULATORY GUIDELINES FOR PHYTOPHARMACEUTICALS

    ABOUT AUTHORS:
    Khandelwal Pankaj, Chirag Sudani*, Parmar Jatin, Prashant Sanghavi, Shifalee Magazine
    Mahatma Gandhi College of Pharmaceutical Sciences,
    Jaipur.
    *patel_chirag75@yahoo.com

  • 30 September 2013
    FILM COATING TECHNOLOGY: AN OVER VIEW

    About Authors:
    G. Sowjanya*, P. Ramaa Bharathi, Dr.A.M.S.Sudhakar Babu
    A.M.Reddy memorial college of pharmacy,
    Narasarao Pet.
    Sowjanya.gedagamma@gmail.com

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