SPECTROPHOTOMETRIC METHOD FOR ESTIMATION OF MEROPENEM AND SULBACTAM SODIUM IN COMBINED DOSAGE FORM BY FIRST ORDER DERIVATIVE METHOD

GPAT courses

Pharma courses

pharma courses

pharma courses




Figure 1: Chemical structure of Meropenem(MERO)


Figure 2: Chemical structure of Sulbactam Sodium(SUL)


Figure 3: Zero order overlain spectra of MERO 10µg/ml and SUL 10µg/ml in 0.1 M KOH


Figure 4: Overlain First Order derivative spectra ofMERO and SUL.

REFERENCES
1.Maryadele. J. O’ Neil. The Merck Index: An Encyclopedia of chemicals, Drugs and Biologicals, 14th edition, Merck and Co., Inc. Whitehouse station. NJ: 1124, 2006.
2.Indian Pharmacopoeia 2010, volume II, 6th edition, Govt of India, New Delhi: The Controler of publication : 1655, 2010.
3.U.S.Pharmacopoeia / NF 2009 volume II, Twinbrook Pathway Rockwillae : The United State Pharmacopoieal Convention : 2714, 2009.
4.Patel N; “Method Development and Validation for the Simultaneous Estimation of Meropenem and Sulbactam Sodium”. CPR, 2(2):480-486, 2012.
5.Srinivasa R.N; “RP- HPLC and Visible Spectrophotometric methods for the Estimation of Meropenem in Pure and Pharmaceutical Formulations”. International Journal of ChemTech Research, 3(2):605-609, 2011.
6.Rao L. V; “Reverse Phase HPLC and Visible Spectrophotometric Methods for the Determination of Meropenem in Pure and Pharmaceutical Dosage Form”. International Journal of PharmTech Research, 4(3):957-962, 2012.
7.Andreas S. L; “Validation of HPLC and UV spectrophotometric methods for the determination of meropenem in pharmaceutical dosage form”. Journal of Pharmaceutical and Biomedical Analysis, 33(5):947-954, 2004.
8.Utpal N; “Estimation of Meropenem in Human Plasma by HPLC-UV and its Application in Comparative Bioavailability Study”, IJPI’s Journal of Analytical Chemistry, 2(3):125-132, 2011.
9.Roger E; “High-Pressure Liquid Chromatographic Assay of Sulbactam in Plasma, Urine, and Tissue”. Antimicrobial agents and chemotherapy, 30(2):231-233, 1986.
10.Kumar K.V, Dharuman J; “RP-HPLC method development and validation for simultaneous estimation of sulbactam and cefoperazone in dosage form and in plasma”. International Journal of pharmaceutical and biological sciences, 1(4): 87-92, 2010.
11.Shrivasta S.M, Singh R.K; “A novel hplc method for simultaneous determination of ceftriaxone and sulbactam in sulbactomax”. International journal of biomedical science, 5(1):37-43, 2009.
12.Ling M.Q; “A Validated Method for Simultaneous Determination of Piperacillin Sodium and Sulbactam Sodium in Sterile Powder for Injection by HPLC”. Journal of Liquid Chromatography & Related Technologies, 26(4):665- 676, 2003.
13.Bello A, Callejon M.O; “Simultaneous determination of rifampicin and sulbactam in mouse plasma by high-performance liquid chromatography”. Biomedical Chromatography, 20(8):748-752, 2006.
14.Siddiqui M.R, Tariq A; “HPLC method for simultaneous determination of cefipime and Sulbactam in supime and biological samples”, International journal of pharmacology, 6(3):271-277, 2010.
15.Sulochana K.N; “HPLC method for simultaneous determination of ampicillin and Sulbactam in biological samples”. Indian Journal of Pharmacology, 27(3):189-192, 1995.
16.Pei Q, Yang G.P, Li Z.J; “Simultaneous analysis of amoxicillin and sulbactam in human plasma by HPLC-DAD for assessment of bioequivalence”. Biomed Life Science, 879(21):2000-2004, 2011.
17.Siddiqui M.R, Abu Tariq; “Development and validation of high performance liquid chromatographic method for the simultaneous determination of Ceftazidime and sulbactam in spiked plasma and combined dosage form¬”. Zydotam American Journal of Applied Sciences, 6(10):1781-1787, 2009.
18.Patel F.M, Dave J.B; “A validated stability indicating high-performance liquid chromatographic method for simultaneous estimation of cefuroxime sodium and sulbactam sodium in injection dosage form”. Chron Young Sci, 3(4):279-285, 2012.
19.The International Conference on Harmonization, Q2 (R1), Validation of Analytical Procedure, Text and Methodology, 2005.

NOW YOU CAN ALSO PUBLISH YOUR ARTICLE ONLINE.

SUBMIT YOUR ARTICLE/PROJECT AT articles@pharmatutor.org

Subscribe to Pharmatutor Alerts by Email

FIND OUT MORE ARTICLES AT OUR DATABASE


 

Pages

FIND MORE ARTICLES