A REVIEW ON MUSSAENDA SPECIES

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Mussaenda 'dona aurora'
Mussaenda 'dona aurora'(sepals) has been investigated for its hepatoprotective and antioxidant activities. The highest activity was observed in the ethyl acetate fraction. The separation of the ethyl acetate fraction gave two iridoids, sanshiside-D and lamalbide. Sanshiside-D exhibited a hepatoprotective activity greater than silimarin as was evidenced by significant reduction of ALT and AST in the serum enzyme levels.

CONCLUSION
Medicinal plants have played an essential role in the development of human culture. Many of the modern medicines are produced indirectly from medicinal plants, for example aspirin. The study of medicinal plants has progressed is in the discovery of bioactive compounds from new promising drug species and understand plant toxicity and protect human and animals from natural poisons.

The genusMussaenda (rubiaceae) is an important source of medicinal natural products, particularly iridoids, triterpenes and flavonoids, carbohydrates ,poly phenols.

Although a number of chemical components described for the Mussaendagenus are also found in other species, the secondary metabolites produced by this genus, particularly the flavonoids make these plants an important source of potential phytotherapeutic and medicinal agents.

Most of the species reported positive for triterpenoids, steroids, flavonoids, glycosides and only a few number of species reported positive for alkaloids and tannins. Many Mussaenda species were reported to possess anti-oxidant, anti-inflammatory in different models, analgesic, antimicrobial, diuretic, antiphlogistic and antipyretic, acute gastroenteritis and dysentery, anti- fertility activity, antiviral property , antibacterial effect rarely for hepatoprotective activity and wound healing activity.

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