PYRIMIDINE AND ITS BIOLOGICAL ACTIVITY: A REVIEW

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Marketed Drugs Containing Pyrimidine Nucleus:-

Anticancer Agents:-


Prazosine: a sympatholytic drug used to treat high blood pressure and anxiety, PTSD, and panic disorder.


CONCLUSON:
The reviewed pyrimidine moiety has shown a wide spectrum of biological activities. The various substituted pyrimidine derivatives have been reported as anti-microbial, analgesic, anti-viral, anti-inflammatory, anti-HIV, anti-tubercular, anti-tumour, anti-neoplastic, anti-malarial, diuretic, cardiovascular agents and also used as hypnotic drugs for the nervous system. Now a day’s Pharmaceutical companies are produced pyrimidine derivatives drugs, such as marketed drugs are mentioned above. The versatile synthetic applicability and biological activity of these heterocycles compounds will help the medicinal chemists to plan, organize and implement new approaches towards discovery of novel drugs.

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