FORMULATION AND EVALUATION OF CHEWABLE TABLETS OF MEBENDAZOLE BY DIFFERENT TECHNIQUES

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Table III.: Comparative evaluation of tablets using different parameter

Parameter

Tablets code

NAG

AG

DC

MAR

Weight of tablet (mg)

513±3.0

513±4.5

513±2.5

---

Bulk density

0.48

0.38

0.58

---

Tapped density

0.55

0.44

0.66

---

Carr’s index

12.88

12.89

12.63

---

Hausner ration

1.14

1.14

1.14

---

Hardness (kg/cm2)

5.2±0.25

5.1±0.10

5.5±0.09

---

Friability test (%)

0.65

0.55

0.25

---

Desintegration time (min)

5

4

3.5

---

Dissolution time cumulative % of drug dissolved in 30 min

81

80.5

87

83.42

Drug content (mg)

99.50

99.20

99.70

--

Assay (%)

97

95

99

--

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