September 2013

The Public Health Foundation of India (PHFI) is a not-for-profit public private initiative that has collaboratively evolved through consultations with multiple constituencies including Indian and international academia, state and central governments, multi & bi-lateral agencies and civil society groups. PHFI is a response to redress the limited institutional capacity in India for strengthening training, research and policy development in the area of Public Health.

The Kerala Public Service Commission is a body created by the Constitution of India.

The Department of Biotechnology, Ministry of Science & Technology (Government of India) has established the Translational Health Science and Technology Institute (THSTI), an autonomous institution, as a part of the interdisciplinary Health Biotech Science Cluster, in the National Capital Region.

The Kerala Public Service Commission is a body created by the Constitution of India.

Applications are invited on prescribed format for the following assignment in a purely time bound research project undertaken in the Department of Life Science of the Institute.

Post: Junior research fellow- 01

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The Council of Scientific and Industrial Research (CSIR) is an autonomous organization under the Ministry of Science & Technology, Government of India. It is amongst the foremost scientific and industrial research set-ups in the world, having state-of-the-art infrastructure and scientific and technical manpower second to none, CSIR covers practically the entire spectrum of scientific and industrial R&D of national and international importance.

The Vision Group on Science and Technology (VGST) was constituted in October 2008 under the Chairmanship of distinguished scientist Prof. C.N.R. Rao, F.R.S., National Research Professor and Chairman - Science Advisory Council to Hon’ble Prime Minister of India. VGST is functioning under the aegis of Department of Information Technology, Biotechnology and Science & Technology, Government of Karnataka.

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About Authors:
Yogesh Yaduwanshi*, Gireesh Mehta, Jitendra Shakyawal, Surya Pratap, Sanjay Singh, Mahaveer Kabra
Department of Pharmacology,
Kota College of Pharmacy, Kota,
Rajasthan India
*yogeshyaduwanshi24@gmail.com

Abstract:
Chemicals are an integral part of our daily lives and are responsible for substantially improving them. Yet chemicals can also endanger our health, even our survival. This report focuses on neurotoxic substances, those chemicals that adversely affect the nervous system. Included among such substances are industrial chemicals, pesticides, therapeutic drugs, abused drugs, foods, food additives, cosmetic ingredients, and naturally occurring substances. Whether a substance causes an adverse health effect depends on many factors, including the toxicity of the substance, the extent of exposure, and an individual's age and state of health. Minimizing public health risks requires knowledge about the properties and mechanisms of action of potentially toxic substances to which humans may be exposed. The assessment includes discussion of industrial chemicals, pesticides, therapeutic drugs, substance drugs, foods, food additives, cosmetic ingredients, and such naturally occurring substances as lead and mercury. It does not include radioactive chemicals, nicotine, alcohol, biological and chemical warfare agents, microbial, plant, and animal toxins, and physical agents such as noise.