January 2013

PharmaTutor
2 January 2013

Multiple vacancies for B.Pharm, M.Pharm, M.Sc, D.Pharm in Production, QC/QA, Technicians @ Alembic Pharma

Alembic Limited, with an established presence in the Indian pharma  industry has a proud, historical track record going back one hundred years. With a turnover in excess of Rs1000 crores today, Alembic Limited is one of India’s leading integrated pharmaceutical companies.

2 January 2013
Opening for Senior Scientist - Quality Assurance in Biocon

2 January 2013
Job as Deputy Manager - IPR in Biocon

2 January 2013
A NOVEL ANTIDIABETIC DRUG: MIGLITOL: A REVIEW

About Authors:
Rahul kumar Singh
M.Pharm (Quality Assurance)
Sr. Officer Quality Assurance at Shreya Life Sciences Pvt. Ltd.,
Roorkee, Uttarakhand
rahulsingh.qa@gmail.com

Abstract
Miglitol, an oral alpha-glucosidase inhibitor, is a desoxynojirimycin derivative that delays the digestion of ingested carbohydrates, thereby resulting in a smaller rise in blood glucose concentration following meals. As a consequence of plasma glucose reduction, miglitol reduce levels of glycosylated hemoglobin in patients with Type II (non-insulin-dependent) diabetes mellitus. Systemic nonenzymatic protein glycosylation, as reflected by levels of glycosylated hemoglobin, is a function of average blood glucose concentration over time. Because its mechanism of action is different, the effect of miglitol to enhance glycemic control is additive to that of sulfonylureas when used in combination. In addition, miglitol diminishes the insulinotropic and weight-increasing effects of sulfonylureas. Miglitol has minor inhibitory activity against lactase and consequently, at the recommended doses, would not be expected to induce lactose intolerance.

2 January 2013
BIODEGRADABLE POLYMERS AND THEIR ROLE IN DRUG DELIVERY

About Authors:
Kotta Kranthi kumar1, V Bhargava Reddy2
Sku college of pharmaceutical sciences S.K.University Anantapur
*kranthikumarkotta@gmail.com

ABSTRACT
In the nature so many polymers are available. With this natural polymers will not shows any interactions with the api. In the drug delivery systems the polymers are plays an important role for the delivery of the drugs. By using the polymers we will deliver the drugs in the targeting points. Now a day this polymers science is the emerging field for the development and invention of new polymers. In the coming years  polymers will plays a vital role in dug delivery.

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1 January 2013
Opening for Junior Research Fellow in University College of Medical sciences

The University College of Medical Sciences (UCMS) was established in 1971 as a Constituent College of University of Delhi. It imparts various medical and paramedical courses. Guru Teg Bahadur Hospital is the associated teaching hospital with 1000 beds.  UCMS is known for its quality research and has a National ranking of 7th based on the number of publications in PubMed indexed journals.

1 January 2013
Agharkar Research Institute invites Research Associate, Research Student

Agharkar Research Institute (ARI) is an autonomous, grant-in-aid research institute of the Department of Science and Technology (DST), Goverment of India. It was established in 1946 by the Maharashtra Association for the Cultivation of Science as MACS Research Institute and renamed as ARI in 1992 in honour and memory of its founder Director, late Professor S.P. Agharkar.

1 January 2013
REVIEW ARTICLE ON ANTIMICROBIAL, ANXIOLYTIC AND MUSCLE RELAXANT ACTIVITY OF ECLIPTA ALBA (BHRINGRAJ)

About Authors:
Nishtha mukherjee
Shri ram institute of technology
jabalpur (m.p.) 482002
Nishthamukherjee210@gmail.com

ABSTRACT: Eclipta alba offers a remarkable activities for curing of many diseases. It has wide range of chemical constituents. Clinical investigations have been done on pharmacological activities like hepatotoxicity, proliferative, diabetic, hypolipedemic etc. Eclipta alba leaves were collected and dried. Furthur aquous and ethanolic extract were prepared and evaluated for anti microbial, anxiolytic and muscle relaxant activity.

1 January 2013
DENDRIMERS FOR NOVEL DRUG DELIVERY: AN OVERVIEW

About Authors:
Roopesh Sachan*1, Prof. Satyanand Tyagi2, Tarun Parashar1, Soniya1, Patel Chirag J*3,Patel Pinkesh3, Rishikesh Gupta4
1*Department of Pharmaceutics, Himalayan Institute of Pharmacy and Research, Rajawala, Dehradun, Uttarakhand, India-248007.
2President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074.
3Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
4Institute of Pharmacy, Bundelkhand University, Jhansi, Uttar Pradesh, India-284128.
*roopeshsachan@gmail.com, +91-9557469989, 9236167104

ABSTRACT:
Nanoparticle drug-delivery systems are the popular ones as are able to increase the selectivity and stability of therapeutic agents. However reticuloendothelial system (RES) uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity restrict the use of these nanostructures. These shortcomings are overcome by surface engineering the dendrimer such as Polyester dendrimer, Citric acid dendrimer, Arginine dendrimer, Glycodendrimers, PEGylated dendrimers, etc.The field of Dendrimers has recently emerged as the most commercially viable technology of this century because of its wide-ranging potential applications in many fields such as: healthcare, electronics, photonics, biotechnology, engineering products, pharmaceuticals, drug delivery, catalysis, electronic devices, environmental issues and nanotechnologies. Dendrimer as a drug delivery agent is a promising, safe and selective drug delivery option.