March 2012

Bharathidasan University established in February 1982, and was named after the great revolutionary Tamil Poet, Bharathidasan (1891-1968). The motto of the University "We will create a brave new world". The University endeavours to be true to such a vision by creating in the region a brave new world of academic innovation for social change"(NAAC, - 2005, p.69). The year 2006-07 is the Silver Jubilee year for this great and vibrant University.

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Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.

ABOUT AUTHORS:
Sudha Talasila^*1, Yamini Pendyala², Deepthi Madhu³, Dr.K.L.Senthil kumar.
^1,2 Department of Pharmaceutics,
Padmavathi College of Pharmacy and Reserch institute,
periyanahalli, Tamilnadu, India.
³ Department of Pharmaceutics, Gitams university,
Visakhapatnam, India.

ABSTRACT
Aim of our present study was to formulate the Gelatin Microspheres Loaded with Lisinopril Dihydrate by using Co-acervation phase separation technique for control prolonged release of drug. Micro-particulate drug delivery of Lisinopril Dihydrate was prepared by using a blend of gelatin-carbopol 934P NF and Gelatin-Sodium alginate as release retardant.Lisinopril Dihydrate Microspheres were formulated by using different drug, gelatin-carbopol and gelatin-sodiumalginate in 6 batches was F1, F2, F3, F4, F5 & F6. All the formulations were investigated for various evaluation parameters like particle size, Bulk density, flow behavior, Entrapment efficiency, percentage yield and in vitro drug release etc. All the formulations showed good flow behavior. SEM study revealed that the spheres were almost spherical in shape with smooth surface. In-vitro drug release study showed that by increasing the polymer concentration the drug release of all the formulations were gradually decreased and the optimized formulation (F6) was able to sustain the drug release for 24 hours. So, it was concluded that gelatin microspheres loaded with Lisinopril Dihydrate can be prepared by Coacervation phase seperation  technique and used for sustaining the drug release for prolonged period of time.

Applications are invited for the posts of Finance & Accounts Officer, Librarian, Professor, Associate Professor & Assistant Professor, which are being recruited on Regular basis in the School of Computational Sciences, Education, Social Sciences (Sub-Centre, Latur ), Social Sciences (University Campus), Technology (Sub-centre, Latur), Mathematical Sciences (Mathematics & Statistics), Physical Sciences, Life Sciences, Earth Sciences, Language & Literature [English,], Media Studies and Pharmacy of this Uni

It’s immense pleasure & proud for us to introduce ourselve as newly established but a prominent company in the field of pharmaceuticals in India. They are dealing with sales and promotion of pharmaceutical products. They are located at Ahmednagar, Maharashtra of India.