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September 2011

Impact of Mycotoxin in the Program Cell Death / Necrosis

About Author: Rinki Verma (Research Fellow)
Center of Experimental Medicine and Surgery,
Institute of Medical sciences,
Banaras Hindu University,
Varanasi, India

Abstract
Genetic instability caused by secondary metabolites produced by fungus. These  mycotoxins are chemical compound which are naturally toxic to cells. Because of ability to generating ROS and RNS caused oxidative stress. Due to their toxicity properties implicate apoptosis and form cancer cell. DNA replication are going to impaired and become damage. Mycotoxins are suppressed tumor suppressing gene and convert proto-oncogene in the oncogene. In this review we explain the control exposure of mycotoxins and provides guidelines to farmers because they are directly contact to these compounds.

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