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Jaipur National University

 

Clinical courses

  • Invites Applications for Professors, Associate Professors & Assistant Professors at Jaipur National University

    Jaipur National University, Jaipur, a Private self- financed University, sponsored by Mahima Shiksha Samiti, came into existence on October 22, 2007, through an Ordinance of the Government of Rajasthan. The University is one of the many institutions of the Seedling Group of educational institutions of the Mahima Shiksha Samiti.

    Invites Applications For The Post of Professors, Associate Professors & Assistant Professors

  • Jaipur National University invites Faculty positions

    Jaipur National University, Jaipur, a Private self- financed University, sponsored by Mahima Shiksha Samiti, Came into existence on October 22, 2007 through an Ordinance of the government of Rajasthan. Jaipur National University is one of the many institutions of the Seedling Group of educational Institutions of the Mahima Shiksha Samiti.

    Invites applications for the posts of Professors/ Associate Professors/ Assistant Professors in the following disciplines

    Post: Professors/ Associate Professors/ Assistant Professors

  • Application are invited for Pharmacist in JNU | 12 Posts

    Jaipur National University, Jaipur, a Private self- financed University, sponsored by Mahima Shiksha Samiti, Came into existence on October 22, 2007 through an Ordinance of the government of Rajasthan. Jaipur National University is one of the many institutions of the Seedling Group of educational Institutions of the Mahima Shiksha Samiti.

  • INDIAN DRUG REGULATORY SYSTEM: MOVING TO A NEW ERA

    About Author:
    Priyank Sharma
    M. Pharm, Drug Regulatory Affairs
    Jaipur National University
    Jaipur, Rajasthan
    Priyank2k4urwith@gmail.com

    Abstract:
    The Pharmaceutical industry represents one of the India’s strength.  The regulation of pharmaceuticals in India is generally seen to be in need of reform, and has been the subject of many official commissions since 1995. Most commentators agree that the state should intervene to prevent untrammeled market forces leading to citizens’ suffering, because adequate information about the costs and benefits of different pharmaceuticals is inaccessible to most users. But in India, a wide range of stakeholders must be considered before changes can be made to the regulatory framework.

  • A REVIEW ON ROLE OF MOLECULAR DESCRIPTORS IN QSAR: A COMPUTATIONAL METHODS APPROACH

    About Authors:
    Rakesh Bhatia*
    School of Pharmaceutical Sciences,
    Department of Pharmaceutical Chemistry,
    Jaipur National University,
    Jaipur-302025 (Rajasthan), India

    *rakesh.mpharm1304@yahoo.com

    Abstract
    Chemical synthesis data and their biological screening have provided a vast amount of experimental data. As a result of that, availability of large amount of biological data information through molecular biology has made drug discovery and development a more complex method. To combat these problems, Quantitative structure-activity relationships (QSAR) emerged as a very useful tool in drug design. QSAR has been applied extensively and successfully over several decades to find predictive models for activity of bioactive agents. QSAR have brought revolution in drug discovery process by thedevelopment of mathematicalrelationships linking chemical structures and pharmacological activity in quantitative manner of series of compounds. Description of the molecular structure, electronic orbital reactivity and the role of structural and steric components has been the subject of mathematical and statistical analysis. Computational drug design method in QSAR is a rapidly growing field which is now a very important component in the discipline of medicinal chemistry. Virtual filtering and screening of combinatorial libraries have recently gained attention as methods complimenting the high-throughput screening and combinatorial chemistry. These chemoinformatic techniques rely heavily on quantitative structure-activity relationships (QSAR) analysis, a field with established methodology and successful history.By characterize a specific aspect of a molecule that is numbers containing structural information derived from the structural representation used for molecules under study called “Molecular descriptors” to find appropriate representations of the molecular structure of drug compoundsto obtain the structure-activity relationships in which these theoretical and computational methods are based, the ability to predict physicochemical, pharmacokinetic and toxicological properties of these leads are becoming increasingly important in reducing the number of expensive methods and late development failures. Thus thereby, QSAR certainly decreases the number of compounds to be synthesized by easing the selection of the most promising candidates. This review seeks to provide a review on role of molecular descriptors in the drug design in QSAR.

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  • RESISTANCE IN ANTIBIOTICS DEVELOPED : MAINLY USED IN PREGNANCY

    About Author:
    Shambhavi Singh
    B.Pharm (IV) School of Pharmaceutical Science,
    Jaipur national university, Jaipur(RAJ.)

    *shambhavisingh3111@gmail.com

    Abstract
    Broad-spectrum antibiotics are prescribed in one third patients for urinary tract infection, and use of third-generation cephalosporins has doubled in the past decade.

    Bacteria in pregnancy frequently produce the risk of pyelonephritis, preterm labour, and low birth weight infants. Commonly prescribed antibiotics such as ampicillin (pivampicillin), amoxicillin, fluroqunin, trimethoprim, and sulphonamide are currently associated with development of a high degree of resistance towards most common pathogen responsible for causing urinary tract infection, Escherichia coli. During the past few decades new researches have been made against development of resistance in antibiotic and new drugs are synthesised. The presumption that if a specific drug is safe for the both pregnant woman and the foetus depends on how widely the drug has been used. A recent survey among general practitioners and obstetricians in confirmed that the beta-lactam antibiotic pivmecillinam and ciphalosporins are the most commonly used agents in the treatment of bacteriuria in pregnancy However, a surprisingly high number of physicians reported that they prescribe TMP/SMX during the first two trimesters in spite of resistance of E. coli and possible adverse effects on the foetus.

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