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Khushbu Singh*1, Chandana Majee2
1 M.Pharm ( department of pharmaceutics)
2 Assistant Professor, department of pharmaceutical chemistry.
Noida institute of engineering and technology, noida
Dendrimers are highly branched and monodisperse macromolecules that display an exact and large number of functional groups distributed with unprecedented control on the dendritic framework. Based on their globular structure, compared to linear polymers of the same molecular weight, dendrimers are foreseen to deliver extraordinary features for applications in areas such as cancer therapy, biosensors for diagnostics and light harvesting scaffolds. Of the large number of reports on dendrimer synthesis only a few have reached commercial availability. This limitation can be traced back to challenges in the synthetic paths including a large number of reaction steps required to obtain dendritic structures with desired features. Along with an increased number of reaction steps come not only increased waste of chemical and valuable starting materials but also an increased probability to introduce structural defects in the dendritic framework.Dendrimer chemistry is one of the most fascinating and rapidly expanding areas of modern chemistry. Nanoparticle drug-delivery systems are the popular ones as are able to increase the selectivity and stability of therapeutic agents. However reticuloendothelial system (RES) uptake, drug leakage, immunogenicity, hemolytic toxicity, cytotoxicity, hydrophobicity restrict the use of these nanostructures. These shortcomings are overcome by surface engineering the dendrimer such as Polyester dendrimer, Citric acid dendrimer, Arginine dendrimer, Glycodendrimers, PEGylated dendrimers, etc. The bioactive agents can be easily encapsulated into the interior of the dendrimers or chemically attached i.e. conjugated or physically adsorbed onto the dendrimer surface, serving the desired properties of the carrier to the specific needs of the active material and its therapeutic applications
Invites applications for Faculty Positions as Professor /Associate Professor/ Assistant Professor @ RKGIT
HLL Lifecare Limited (formerly Hindustan Latex Limited) India’s leading manufacturers and marketers of Contraceptive, Health Care and Pharma products is a Mini Ratna Company under the Ministry of Health & Family Welfare, a Govt. of India Enterprise, with Seven manufacturing units and marketing offices throughout the country.
Opportunity for Director, Professor, Associate Professor, Assistant Professor in IIMT Group of Colleges
The IIMT Group of colleges was founded in the year 1994. Since then the group has grown impressively and achieved exemplary recognition from corporate, academia, and professional circles.
At IIMT we are committed to provide a value driven culture along with creating a professional environment. The IIMT as a group is large and diversified group and imparts knowledge in field of Engineering, Management, Medical Sciences, Hotel Management, Nursing, Education, Law etc. The IIMT group has more than 1330 highly qualified and experienced faculty members in their respective functional areas. IIMT boasts of having more than 20,000 students in various courses in five campuses.
Vishwa Deepak kumar
Departement of Pharmacy,
IEC group of institution,
Greater Noida (U.P), Pin- 201301
Pharmacovigilance is an important and integral part of clinical research. Pharmacovigilance is “defined as the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects, particularly long term and short term adverse effects of medicines. This addresses what exactly is Pharmacovigilance? What do we know of its benefits and risks, challenges and the future hold for pharmacovigilance in Indian medicine. Here the main focus on the aims and role of Pharmacovigilance in medicines regulation and their Partners. This article describes and discusses the National programme of pharmacovigilance and centre in India. There role in collecting the reports ADRs of medicines. Further effectiveness and risk assessments of therapies are been discussed. The important role played by health care professional, pharmaceutical industries, media, and programmes carried by WHO. Finally the conclusion describes the major challenges and achievements for the future pharmacovigilance programmeand toxicity is not socritical if botanicals are used in traditional forms (Harborne., 1998).
New Horizons in Pharmacy Education at Apeejay Stya University, Gurgaon | Admission Open for M.Pharm, Ph.D, MBA
The School of Pharmaceutical Sciences, Apeejay Stya University offers highly advanced and internationally aligned post-graduate courses in Pharmacy Education. The following courses are on offer:
Neha singh*1, Chandana Majee2
1.M.Pharm ( Department of Pharmaceutics)
2.Assistant Professor, Departmrnt of pharmaceutical chemistry.
Noida Institute of Engineering and Technology, Noida
In order to achieve a successful colon targeted drug delivery system, a drug needs to be protected from degradation, release and/or absorption in the upper portion of the gastrointestinal tract (GIT) and then ensure abrupt or controlled release in the proximal colon. Such a system can be formulated by utilizing microbial triggering degradation of polymer coating/ gastro intestinal (GI) transit time (time dependent)/ pH dependent approach etc. But unfortunately it has been found that colonic microflora, GI transit time and pH varies considerably inside a human system by several factors, in addition to this the native biodegradable polysaccharides which are used widely for the microbial triggering colonic drug delivery system (CDDS), are having high aqueous solubility on account of which a single unit colon targeted drug delivery systems may suffer from dose dumping due to overall catastrophic failure of the film around a monolith, which would then release the whole drug, that may lead to drastically compromised systemic drug bioavailability or loss of local therapeutic action in the colon. This review emphasizes some of the causes which make a single unit dosage form unsuitable for targeting to colon by using microbial triggering/GI transit time/pH dependent approach, and at the same time discusses researches which have been carried out to alleviate these problems by utilizing multiparticulate combined approaches.
The Jaypee Group of Companies has consistently displayed full awareness of its social responsibilities through the Jaiprakash Sewa Sansthan (JSS), a ‘not for profit’ Trust. The Group believes that Education is the cornerstone to economic development and which alone can assist build India into a developed nation.
With the thought of using technology and management effectively, thevisionary founder of the JSS, Shri Jaiprakash Gaur set up 3 technical institutes of higher education to host the best of faculty, students and educational infrastructure to ensure creation, generation, dissemination and application of knowledge to mould the world leaders of tomorrow.
Walk in Interview for Business Development Executives - Healthcare Education & Training in Cliniminds
Cliniminds was established in year 2004, by a group of professionals from Clinical Research, Pharmaceutical industry and Healthcare industry with rich and varied experience at senior management levels. Cliniminds offers Educational & Training Programs to develop the skill capacity in the health sciences domain. Cliniminds is an innovative health sciences educational and training institute providing a wide range of clinical trials, regulatory, phamracovigilance, data management and other job oriented training programs. We also provide training and continuing medical education solutions to the, pharmaceutical companies, CROs, hospitals, and healthcare companies globally.
The Central Council for Research in Homoeopathy (CCRH), New Delhi, an autonomous body under the Department of AYUSH, Ministry of Health and Family Welfare, Government of India intends to engage the following categories of personnel on contract basis for posting in its peripheral Institutes/Units located throughout the country. The engagement will be purely on contract basis and selection will be made through Walk-in- Interview:-
Post: Senior Research Fellow (Chemistry)