Kerala

3 February 2013

FORMULATION AND EVALUATION OF DRY POWDER INHALERS OF BUDESONIDE FOR PULMONARY DELIVERY

About Authors:
Neethu.R.R
Uthradam
Kannayamkodu
Chenkikunnu
Kilimanoor.P.O, Trivandrum dist, Kerala 695601
neethalekshmi87@gmail.com

Abstract:
Budesonide is a corticosteroid, used in the treatment of inflammatory conditions such as asthma and COPD. The present study was undertaken with the aim to formulate and evaluate dry powder inhalers of Budesonide for pulmonary delivery. Dry powder inhalers of Budesonide were prepared using different concentrations of fine lactose and magnesium stearate by Geometric dilution method. The drug-carrrier compatibility study was carried out by FT-IR studies. A total of eleven batches were formulated and evaluated for physical appearance, average fill weight, flow properties, particle size analysis, content uniformity, moisture content and assay. In-vitro drug deposition studies were carried out by using Modified Twin Stage Impinger (TSI) apparatus. Of all eleven batches, the formulation F4, comprising of fine lactose 30% was found to be the best having comparatively higher fine particle fraction (FPF) of 25.32%. The result indicated that the amount of drug that reaches in the lung was higher for formulation F4. Further invivo safety and deposition studies on suitable animal models and human volunteers will give better insight for clinical applications of the Budesonide DPI.

28 January 2013

PHARMACOLOGICAL EVALUATION OF ETHANOLIC EXTRACT OF EMBELIA RIBES: (VIDANGA) FRUIT IN EXPERIMENTAL ANIMAL MODELS

About Authors:
Saritha.A.Surendran*, Asa Samuel
*St. James College of Pharmaceutical Sciences,
Chalakudy, Kerala
*sarithaasurendran@gmail.com

ABSTRACT
Analgesics are the drug that selectively relieves pain by acting in the CNS or peripheral pain mechanism without significantly altering consciousness. They are classified into centrally acting analgesics and peripherally acting analgesics. Embelia ribes seeds was collected and extracted by continous hot percolation process using ethanol. Phytochemical analysis of the extract was preformed, screened and compared the analgesic activity of the extract with Pentazocine. Animal treated with ethanolic extract of Embelia ribes was showed an increased reaction time compared to control group. Ethanolic extract was showed significant reduction in algesia when compared with pentazocin.

10 January 2013

Application invited for the post of Junior Research Fellow - Chemistry in Indian Institute of Science Education and Research

Indian Institute of Science Education and Research, Thiruvananthapuram (IISER-TVM) is dedicated to scientific research and science education of international standards. Traditionally, teaching has been segregated from research in undergraduate science curricula in our country. IISERs were established by the Ministry of Human Resource Development, Government of India, to bridge this dichotomy. IISER-TVM started functioning in August 2008.

27 December 2012

Application are invited for Pharmacist Grade II Kerala Public Service Commission

The Kerala Public Service Commission is a body created by the Constitution of India.

27 December 2012

Opportunity for Area Sales Manager in Ajanta Medicals

Ajanta Medicals P. Ltd. is privately owned company established 30 years back at Mumbai. Company has acquired a reputation as a manufacturer of quality Ayurvedic products. The company has a distribution network in Mumbai, Gujarat and now willing to spread on pan India basis.

Post: Area Sales Manager

26 December 2012

Franco-Indian Pharmaceuticals invites Regional Sales Managers, Area Sales Managers, Trainee Medical Representatives

Franco-Indian Pharmaceuticals Pvt. Ltd., a name that stands for quality and innovation, is one of the major players in the Pharmaceutical Industry in India.
Our innovative, value added products improve the quality of life of people and ease their sufferings and help them to enjoy, longer, healthier and more productive lives.

25 December 2012

Job as Research Associate in Rajiv Gandhi Centre for Biotechnology

The Rajiv Gandhi Centre for Biotechnology (RGCB) is a growing phenomenon. Located in Thiruvananthapuram, the capital city of Kerala, RGCB began in 1990 amongst humble surroundings as a small charitable society called the Centre for Development of Education, Science and Technology (C-DEST).

18 December 2012

Application are invited for the post of Junior Research Fellow in Jawaharlal Nehru Tropical Botanic Garden And Research Institute (JNTBGRI)

Application are invited from suitable candidates for the selection of Junior Research Fellow (One) in the project entitled “Biflavonoids from Garcinia species- Chemical, Molecular and Pharmacological Evaluation” (A-144) at Jawaharalal Nehru Tropical Botanic Garden and Research Institute, Palode, Thiruvananthapuram. Details are given below

17 December 2012

Sree Chitra Tirunal Institute for Medical Sciences & Technology invites Apprentice —Microbiology

Sree Chitra Tirunal Institute for Medical Sciences & Technology (SCTIMST), Thiruvananthapuram is an Institute of National Importance established by an Act of the Indian Parliament and under the 2 administrative control of the Department of Science and Technology, Government of India.

14 December 2012

Job as Business Development Executive in Triune Ventures

Kerala Based Pharma and health care Company. Incorporated in 2012 Managed by Professionals.
we are looking for our team members more than employees.

Post: Business Development Executive

[adsense:336x280:8701650588]