Pharmacognocy Articles

ROLE OF CHROMATOGRAPHY IN EVALUATION OF HERBAL DRUGS: A SHORT REVIEW

About Author:
Alimuddin Saifi
N.K.B.R. College of Pharmacy & Research Centre,
Meerut
asaifi2005@gmail.com

Abstract
Herbal drugs are accepted as important therapeutic agents for the treatment of many diseases. The development of authentic analytical methods which can reliably profile the phytochemical composition, including quantitative analyses of marker/bioactive compounds and other major constituents, is a major challenge to scientists. Pharmacognostical analysis of medicinal herbs remain challenging issues for analytical chemists, as herbs are a complicated system of mixtures. Analytical separation techniques for example high performance liquid chromatography (HPLC), gas chromatography (GC) and mass spectrometry (MS), High Performance Thin Layer Chromatography (HPTLC) etc. among the most popular methods of choice used for quality control of raw material and finished herbal product.

INDUSTRIAL PREPARATIONS AND STANDARDIZATION OF HERBAL MEDICINES

About Authors:
Kapil Sharma*, Priyanka Sharma
Yaresun Pharmaceutical Pvt. Ltd.,
India.
*pharma_kapil@rediffmail.com

ABSTRACT
Herbalism is a traditional medicinal or folk medicine practice based on the use of plants and plant extracts. Many plants synthesize substances that are useful to the maintenance of health in humans and other animals because herbal medicine have harmless advantages. Humans, and even neanderthals, have used plants to treat their ailments for at least tens of thousands of years; most likely even longer than that. The first written accounts of the use of herbs originate in china, although all other civilizations from the ancient world were using plants as natural remedies for their ailments. Western herbal medicine dates back to ancient greece and its famous doctors like hippocrates and galen.The 15th to 17th centuries were the most popular time for herbalism in europe. Herbal remedies are still relatively popular today, mainly due to the fact that they are regarded as harmless because they are natural. So this paper describe basic information  involved in preparation of herbal remedies for internal use and for external useand gives a detail account about standardization and evaluation in formulations of herbal drugs.

PHARMACOGNOSTIC AND PRELIMINARY PHYTOCHEMICAL STUDY OF ALSTONIA SCHOLARIS FRUITS (L) R.BR. FAM: APOCYNACEAE

About Authors:
Sanober Parveen*, Maju Vyas Singh
Delhi institute of Pharmaceutical Sciences & research University (DIPSAR), Delhi.
*sanober.parveen@gmail.com

Abstract
The present study was aimed Pharmacognostic and preliminary phytochemical study of the fresh fruits of Alstonia scholaris, belonging to family Apocynaceae.The pharmacognostic investigation were carried out in terms of macroscopic, microscopic and physical parameters. The extract obtained after successive Soxhlet extraction of dried fruit using n-hexane, chloroform, methanol and water were subjected to a preliminary phytochemical screening which revealed the presence of alkaloids, carbohydrate, glycoside, terpenoids and flavanoids.

EVALUATION OF ANTHELMINTIC ACTIVITY OF ETHANOLIC ROOT EXTRACT OF ALLOPHYLUS SERRATUS.

About Authors:
A.SRILAKSHMI*, AMRUTHA R.E, N.KRISHNA SREE
Department of Pharmacology
P. Rami Reddy Memorial College of Pharmacy,
Andhra Pradesh, India.
*amrutharamapuram@gmail.com

Abstract:
Present study was aimed to evaluate the anthelmentic activity of ethanolic extract of Allophylus serratus against Indian earthworms Pheritima posthuma. The various concentrations of ehanolic extract of Allophylus serratus were tested for paralysis time and death time of the worms. Results revealed that all the concentrations of Allophylus serratus possess anthelmentic activity in a dose dependant manner. Potency of the test samples was found to be inversely proportional to the time taken for paralysis/death of the worms. The activities were comparable with the reference drug Albendazole(20mg/ml). Among the various concentrations of extracts 400mg/ml dose was found to possess promising anthelmentic activity in comparison to other extracts like 100mg/ml,200mg/ml. Phyto constituents of ethanolic extract of Allophylus serratus were found to be Flavonoids, Phenolic compounds,steroids,tri-terpenoids, Glycosides. The present study therefore justifies its use in the folklore remedies as an anthelmentic drug of natural origin.

A STUDY ON ANTI-DIARRHOEAL ACTIVITY OF FRUIT EXTRACTS OF CARICA PAPAYA (CARICACEAE) LINN. IN RATS

About Authors:
S. Mahboob Ahmad, T.S Gouda
V.L. College of pharmacy,
Raichur, Karnataka-58410
*syed.ahmad007@yahoo.com

Abstract:
The alcoholic and aqueous extracts of fruit of Carica papaya (Caricaceae)was investigated for anti-diarrhoealactivity in albino Wistar rats. The alcoholic and aqueous extracts was administered by the oral route at a concentration of 100, 200 and 400 mg/kg showed the significant dose dependent anti-diarrhoeal activity in Castor oil induced diarrhea and Magnesium sulphate induced diarrhea. Anti-diarrhoeal activity of the tested extracts was comparable with that of the standard drug Loperamide 3 mg/kg. The results lend support to the traditional use of C.  papaya in the treatment of diarrhoeal diseases.

A REVIEW ON MIMOSA PUDICA: A USEFUL WEED

About Authors:
Manu Arora1*, Amanpreet Singh2
School of Pharmacy & Emerging Sciences,
Baddi University of Emerging Science & Technology,
Makhnumajra, Baddi, Distt. Solan,
Himachal Pradesh-173205, India.
*manu_cognosy@yahoo.co.in

ABSTARCT
Mimosa pudica is a weed which is commonly known as chuemue (touch me not) belongs to the family Leguminaceae.  It is found in moist and waste places. Chuemue shows nyctynastic and seismonastic movement. All parts of this plant possess different medicinal properties like dysentery, leprosy, asthma, sedative, emetic and tonic. Its aerial parts contain different secondary plant metabolites like tannins, alkaloids, glycosides, Flavonoids and saponins. This review shows presence of secondary plant metabolites and its ethnopharmacological uses.

ANTIMICROBIAL STUDIES OF METHANOL AND ETHANOL EXTRACTS (SOXHLET EXTRACTION) OF FENUGREEK (TRIGONELLA FOENUM)

About Author:
Tarika Priya
SLC's college of pharmacy. JNTUH
Hyderabad-500076
a4aryatarikapriya@gmail.com

1. Abstract
The aim of study was to screen the antibacterial and antifungal activities of methanol and ethanol extracts of fenugreek seed (Trigonella foenum). Crude extracts of the seeds with methanol and ethanol were screened for antibacterial activities against two gram positive pathogenic bacteria – Bacillus subtilis, Staphylococcus aureus and against two gram negative pathogenic bacteria – E.coli, klebsiella. The antibacterial activity was performed using cup-plate method. The extracts were prepared using soxhlet extraction method. Methanol extract showed activity against E.coli and Klebsiella were as ethanol extract showed activity against Staphylococcus and Bacillus spp.,

The anti fungal activity was also screened against Aspergillus niger. Both the extracts showed good activity against the fungi.
The results obtained in the present study suggest that the extracts revealed a significant scope to develop a novel broad spectrum of antibacterial herbal formulations.