Andhra Pradesh

Osmania University, established in 1918, is the seventh oldest in India, the third oldest in south India and the first to be established in the erstwhile princely state of Hyderabad. Throughout its existence of over eight decades, it has shown remarkable progress and sustained an integrated development of all faculties. It has significantly contributed to the academic and economic development of not only the region but also of the Country.

Mylan ranks among the leading generic and specialty pharmaceutical companies in the world and provides products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios supported by a robust product pipeline; operates one of the world’s largest active pharmaceutical ingredient manufacturers; and runs a specialty business focused on respiratory, allergy and psychiatric therapies.

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

ABOUT AUTHORS:
A.Anil kumar, K.Surekha, M.Sujatha Kumari
Department of Pharmaceutics
Vikas college of pharmacy, Vissannapeta, 521215
*anilkumar.adi@gmail.com

ABSTRACT:
The objective of the present study of Diclofenac sodium was to treat inflammatory bowel disease in colon.   Treatment for IBD is a long term therapy the colon drug delivery system of Diclofenac sodium to the colon provides the following benefits. Avoidance of first pass metabolism, to target local site. The tablet formulation of Diclofenac sodium provides time controlled release to treat the nocturnal symptoms of pain in colon.  The formulation is administered in the night at 10 pm the action will be start early morning 3’0 clock Symptoms that are experienced in early morning hours should be avoided to maintain the lag period of drug release 5hrs. To maintain lag time the best method is pulsein cap drug delivery system and it is high expensive, poor in vivo correlation. Due to cost effectiveness and poor in vivo correlation we preferred to target colon as tablet dosage form. In the present study, the polymer selected as Guargum. Granules were prepared by wet granulation technique using Guargum in different ratios (drug: polymer) FG₁ (1:0.25), FG₂(1:0.5), FG₃(1:0.75), FG₄(1:1), FG₅(1:1.25). To perform the interaction studies by IR spectra studies. To study the influence of polymer concentration on the Diclofenac sodium release from tablets. The prepared tablets were evaluated for different physical parameters and dissolutions studies were performed in 3 dissolution mediums like 0.1N hydrochloric acid for 2hr, pH 7.4 for 3hr, pH 6.8 up to 24hrs. Among all these formulations FG₄ formula (1:1) showed 98% up to 24 hrs drug release. The release mechanisms of all formulations are diffusion controlled conformed from higuchis plot, thus the present study concluded that drug and guar gum (1:1) ratio for fulfill to target local site for colon drug delivery system.

Bhagwan Mahavir Medical Research Centre, Hyderabad is organizing the National seminar on “Emerging trends, challenges and innovative approaches in Clinical Research in India” from 27th to 28th April, 2013 in connection with Mahavir Jayanthi.

The All India Council for Technical Education (AICTE) was established by an Act of Parliament (No. 52 of 1987) with a view to provide proper planning and coordinated development of the technical education system throughout the country, the promotion of qualitative improvements of such education in relation to planned quantitative growth and the regulation and proper maintenance of norms and standards in the technical education system and for matters connected therewith.

The Training and Development effort at Colgate-Palmolive is a direct outcome of the Individual Development Plan and the Business need. The business critical and individual specific needs are identified every year and a training needs inventory is drawn up.