Kanpur

Bengal Chemical & Pharmaceutical Works Ltd.(BCPW)  is precursor of the present Company, Bengal Chemicals & Pharmaceuticals Ltd (BCPL).  Acharya P C Ray  took a rented house at 91 Upper Circular Road, Calcutta and started business with a meager capital of Rs 700.00. Since inception of the Company he was very much quality conscious and produced various products of British Pharmacopoeia standard.

About Authors:
Sanjay Kumar Yadav^*1, Anjana Yadav¹, Shahana Majumder^2
*1Dept of Pharmaceutical Chemistry, B.B.S. Institute of Pharmaceutical & Allied Sciences, Greater Noida, (U.P.), India
¹Dept of Biotechnology, Chhatrapati Sahu Ji Maharaj University, Kanpur, (U.P.), India
²Dept of Biotechnology, Sharda University, School of Engineering and Technology,
Greater Noida, (U.P.), India
*sanjay_yadav3333@yahoo.co.in

ABSTRACT
Viruses are pathogens with an extremely narrow host range. Their phylogenetic origin is vague, tough it has always been considered that viruses are genes that became vagrant after having excluded themselves of the host’s or a related species’ genome (Anderson et.al., 2004). Viruses are usually units consisting of nucleic acids and coat proteins called capsids. Viroids consist only of RNA, i.e. they contain no protein at all. Except for a few cases, Viruses have no energy metabolism of their own. Consequently, they cannot perform syntheses and are thus unable to replicate themselves. Depending on their host species, it is distinguished between plant viruses multiplying almost exclusively within plant cells, bacterial viruses (bacteriophages) that depend on living bacteria, and animal viruses. The genetic information of viruses is either encoded by single-stranded RNA (Most plant viruses), double-stranded RNA (Wound tumor viruses), single-stranded DNA (Gemini viruses) or double stranded DNA (Cauliflower mosaic virus). Based on the shape of the viruses particle, it is distinguished between rod shaped and icosahedral viruses with a capsid that seem almost spherical. Viruses’ cause many disease in humans of international importance for example  smallpox polio, hepatitis etc. viruses cause also many important plant disease and are responsible for huge loss in crop production and quality in all part of the world. Around 25 years ago, when genomic properties of geminiviruses were studied, many scientists regarded them as ‘friends of humans’, because of their  potential as gene transfer vectors in plant genetic engineering and non-harmful effects on host plants. But far from being friends, these viruses have now emerged as foes and are a serious threat to world agriculture now. Increase in international commodity trade, intercontinental transportation networks and a changing global climate have contribute to the spread of this virus and its whitefly vector (Moffat et.al.,1999).

About Authors:
Rawat Pinki^1*, Rawat Preeti², Kumar Piyush³ Kanoujia Jovita³, Singh Sangeeta ¹
1. Institute of Pharmaceutical Science and Research, Unnao, U.P., India.
2.  L.T.R. College Of Technology, Meerut, U.P., India.
3. Curadev Pharmaceuticals Ltd., Kanpur, U.P., India.
*pnkrawat@gmail.com

Abstract:
Selective estrogen receptor modulators, called SERMs for short, blocks the naturally circulating estrogen in breast tissues and other estrogen-sensitive tissues in the body. Each estrogen receptor has a slightly different structure, depending on the kind of cell it is in. If a SERM binds to a estrogen receptor, there is no site available for estrogen to bind and it can't attach to the cell. SERMs are called "selective" because they bind to particular estrogen receptors. This selective binding action is sometimes called estrogen inhibition, or estrogen suppression.

Olefia Biopharma Limited, We would like to introduce ourselves as one of the most rapidly emerging FMCG Company in various fields of Pharmaceutical, Cosmetics, Ayurvedics / herbals and biotech.

About Author:
Mr. Jagmohan Rai Agarwal,
M.Pharm (1968), Industrial experience SSI sector, nearly 37 years,
retired from own Industry (2004),
Founder President of M.P.Pharmacy Graduates’ Association (MPGA),
Ex President: M.P.Pharmaceutical Manufacturers’ Organisation (MPPMO),
Founder President : M.P. Small Scale Drug Manufacturers’ Association (MPSDMA),
Ex President Indian Pharmaceutical Association, M.P. State Branch, Indore (IPA),
Ex Vice Chairman Confederation of Indian Pharmaceutical Industries (SSI) (CIPI)
Recently submitted thesis for award of  Ph.D. on title “Enforcement of Drug Laws-Globalization vis-à-vis Indian Drug Laws”
(Email: sharda_jollo@yahoo.co.in)

About Author:
Mr. Jagmohan Rai Agarwal,
M.Pharm (1968), Industrial experience SSI sector, nearly 37 years, retired from own Industry,
Founder President of M.P.Pharmacy Graduates’ Association,
President: M.P.Pharmaceutical Manufacturers’ Organisation,
Founder President : M.P. Small Scale Drug Manufacturers’ Association,
President Indian Pharmaceutical Association, M.P. State Branch, Indore,
Recently submitted thesis for award of  Ph.D. on title “Enforcement of Drug Laws-Globalization vis-à-vis Indian Drug Laws”
(Email: sharda_jollo@yahoo.co.in)

Quality of Pharmaceuticals has been a concern of the World Health Organisation (WHO) since its inception. The setting of global standards is requested in Article 2 of the WHO constitution which sites as one of the organisation’s functions that it should develop, establish and promote International standards with respect to food, biological, pharmaceuticals and similar products.

Campbell (US FDA) was the first leading architect of the present Federal Food, Drug and Cosmetics Act passed in 1938. He differed sharply with ‘Willey’ in his belief that Court proceedings were not the only proper way to secure compliance.