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  • Fresh understanding of ageing in the brain offers hope for treating neurological diseases

    Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on ageing processes in the brain. By linking the increased presence of specialised immune cells to conditions such as Alzheimer’s disease and traumatic brain injury for the first time, they have unearthed a possible new target for therapies aimed at treating age-related neurological diseases.

  • DNA Repair Discovery Could Improve Biotechnology

    Veterinarian, immunologist, and molecular geneticist Dr. Kathy Meek and her team from the Michigan State University College of Veterinary Medicine have made a discovery that may have implications for therapeutic gene editing strategies, cancer diagnostics and therapies, and other aspects of biotechnology.

  • Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy : Study

    Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from happening, according to new research from UTHealth Houston.

    The study, led by Sandipan Pati, MD, associate professor in the Department of Neurology with McGovern Medical School at UTHealth Houston, was recently published in NEJM Evidence, a publication of the New England Journal of Medicine.

  • Gambia children deaths are associated with syrup made by Maiden Pharmaceuticals, says US CDC

    Centers for Disease Control and Prevention (CDC) US researchers said that the Gambia children deaths are associated with syrup made by Maiden Pharmaceuticals. Their investigation strongly suggests that medications contaminated with diethylene glycol (DEG) or ethylene glycol (EG) imported into The Gambia led to this acute kidney injury (AKI) cluster among children.

  • Tablet-based screening doubles detection of psychosis symptoms in youth

    Asking patients to take a short survey on a tablet before their appointments may help mental health providers identify young people at risk of psychosis. A UC Davis Health study found that when patients took a 21-question pre-visit survey, more than twice as many were identified at risk of psychosis compared to those who did not complete the survey.

  • Establishment of a highly sensitive detection method for imidazole dipeptide oxidation derivatives

    Antioxidants discovered in meat! Osaka Metropolitan University researchers developed a new protocol for selective and highly sensitive detection, discovering five types of 2-oxo-imidazole-containing dipeptides(2-oxo-IDPs) using mass spectrometry. The 2-oxo-IDPs, present in living organisms, exhibit very high antioxidant activity, and were found to be abundant in meat including, beef, pork, and chicken.

  • The drug fasudil is found to reverse key symptoms of schizophrenia in mice

    A team from Nagoya University in Japan used the drug fasudil to reverse two common symptoms associated with schizophrenia: reduced density of pyramidal neurons and cognitive dysfunction associated with methamphetamine treatment. Their findings, which were published in Pharmacological Research, suggest new therapeutic approaches for treating schizophrenia patients.

  • NIH RECOVER research identifies potential long COVID disparities

    Black and Hispanic Americans appear to experience more symptoms and health problems related to long COVID(link is external), a lay term that captures an array of symptoms and health problems, than white people, but are not as likely to be diagnosed with the condition, according to new research funded by the National Institutes of Health.

  • Toxic protein linked to muscular dystrophy and arhinia

    Researchers at the National Institutes of Health and their colleagues have found that a toxic protein made by the body called DUX4 may be the cause of two very different rare genetic disorders. For patients who have facioscapulohumeral muscular dystrophy (FSHD), or a rare facial malformation called arhinia, this research discovery may eventually lead to therapies that can help people with these rare diseases.

  • Oral bacteria may increase heart disease risk

    Infection with a bacterium that causes gum disease and bad breath may increase the risk of heart disease, shows a study published today in eLife.

    The study suggests another potential risk factor that physicians might screen for to identify individuals at risk of heart disease. It may also indicate that treatments for colonisation or infection with the oral bacterium Fusobacterium nucleatum may help reduce heart disease risk.

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