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  • Harnessing big data helps scientists hone in on new antimicrobials
    17 July 2024

    Harnessing big data helps scientists hone in on new antimicrobials

    Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics.
  • 12 July 2024
    Distinct T-cell signatures observed at different stages of type 1 diabetes development
    A study conducted at the University of Eastern Finland found distinct signatures in CD8-positive T cells in blood samples from children with newly diagnosed type 1 diabetes and in autoantibody-positive children who later developed type 1 diabetes. The study was published in the journal Diabetes.
  • 12 July 2024
    Phage-Derived Enzyme Targets E. faecalis Biofilms to Mitigate Acute Graft-Versus-Host Disease

    Acute graft-versus-host disease (aGVHD) is a medical condition that occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). The pathogenesis of aGVHD is influenced by gut dysbiosis and Enterococcus domination. Researchers from Japan recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.

  • 12 July 2024
    Sleep timer for immune cells discovered
    In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus-infected cells but are inactive. A team from the Technical University of Munich has discovered that cells in blood vessels in the liver start a sleep timer that switches off immune cells. Targeting this mechanism could be a starting point for immunotherapies.
  • 10 July 2024
    Nerve damage from cancer treatment can be predicted

    Many women treated for breast cancer using taxanes, a type of cytostatic drug, often experience side effects in the nervous system. Researchers at LiU have developed a tool that can predict the risk level for each individual. The tool could help doctors adapt treatment to avoid persistent side effects in those at the greatest risk. 

  • 6 July 2024
    Drugs that kill zombie cells may benefit some older women, but not all, Mayo Clinic study finds
    Drugs that selectively kill senescent cells may benefit otherwise healthy older women but are not a one-size-fits-all remedy, Mayo Clinic researchers have found. Specifically, these drugs may only benefit people with a high number of senescent cells, according to findings published today in Nature Medicine.
  • 6 July 2024
    Low-dose aspirin could help prevent pregnancy complications caused by flu infections
    A world-first study has found low-dose aspirin may treat flu-induced blood vessel inflammation, creating better blood flow to the placenta during pregnancy.
  • 1 July 2024
    Breakthrough research makes cancer-fighting viral agent more effective
    Researchers from Aarhus University have made a significant breakthrough by discovering that the drug 4-OI can enhance the effectiveness of a cancer-fighting viral agent. This may lead to treatment of cancers that are otherwise resistant to therapies.
  • 1 July 2024
    Study reveals why AI models that analyze medical images can be biased
    Artificial intelligence models often play a role in medical diagnoses, especially when it comes to analyzing images such as X-rays. However, studies have found that these models don’t always perform well across all demographic groups, usually faring worse on women and people of color.
  • 27 June 2024
    New Approach Accurately Identifies Medications Most Toxic to the Liver
    The current method for assessing medication-related liver injury is not providing an accurate picture of some medications toxicity or lack thereof to the liver, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Classification of a medication’s potential to damage the liver, termed hepatotoxicity, has been historically determined by counting individual reported cases of acute liver injury
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