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  • Changing Cholesterol over Time Tied to Risk of Dementia
    30 January 2025

    Changing Cholesterol over Time Tied to Risk of Dementia

    Older adults whose cholesterol changes over time may be more likely to develop dementia than people whose cholesterol is stable, regardless of the actual cholesterol level, according to a study published in the January 29, 2025, online issue of Neurology®, the medical journal of the American Academy of Neurology.

  • 28 January 2025
    Combination of dual-targeted therapies and chemotherapy shows high response rates in BRAF-mutated metastatic colorectal cancer
    Patients with metastatic colorectal cancer harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the Phase III BREAKWATER trial led by researchers at The University of Texas MD Anderson Cancer Center.
  • 28 January 2025
    Iowa researchers study effects of cholesterol-lowering drugs on kidney function
    Statins, a class of cholesterol-lowering drugs, have no effect on kidney function, a research team led by the University of Iowa has found. The research team, led by clinical professors Michelle Fravel and Michael Ernst, in the College of Pharmacy, examined the association between statin use in older adults and changes in two important indicators of kidney function estimated glomerular filtration rate and urine albumin-to-creatinine ratio.
  • 24 January 2025
    mRNA-activated blood clots could cushion the blow of osteoarthritis

    University of Wisconsin-Madison researchers have developed a promising technique for treating osteoarthritis using therapeutic blood clots activated by messenger RNA.

    Osteoarthritis is the most common form of arthritis, affecting roughly 33 million adults in the United States, according to the Centers for Disease Control and Prevention. It occurs when cartilage in key joints like the knees and hips deteriorates, causing pain and stiffness and impeding mobility.

  • 24 January 2025
    A chain reaction : HIV vaccines can lead to antibodies against antibodies
    Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.
  • 23 January 2025
    Researchers make breakthrough in bioprinting functional human heart tissue

    Researchers at University of Galway have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development.

  • 23 January 2025
    Green Tea-Based Adhesive Films Show Promise as a Novel Treatment for Oral Mucositis
    Green tea shines as a natural powerhouse of antioxidants, with catechins leading the charge among its polyphenols, which protect cells from oxidative stress. These powerful compounds neutralize harmful free radicals generated during cancer treatment. The anti-inflammatory properties of green tea can alleviate oral mucositis, a painful inflammation of the mouth lining often caused by chemotherapy and radiation.
  • 22 January 2025
    Researcher Identifies PICH Protein as Key Player in Preventing Chromosome Breakage Linked to Cancer
    Researchers at The University of Hong Kong have made an exciting discovery about how human cells protect DNA during cell division, offering new insights into combating diseases such as cancer. Led by Professor Gary Ying Wai CHAN from the School of Biological Sciences, Faculty of Science, and Professor Ken Hoi Tang MA from the Department of Pathology, LKS Faculty of Medicine, the research uncovers the vital role of a protein called PICH in preventing genetic errors that can lead to diseases such as cancer. Their findings were recently published in the journal Nucleic Acids Research.
  • 21 January 2025
    A major advance in biology combines DNA and RNA and could revolutionise cancer treatments
    Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA epigenetics comes in : a series of mechanisms that act as markers on genes, to control their activity without modifying the DNA or RNA sequence itself.
  • 21 January 2025
    New study paves way for immunotherapies tailored for childhood cancers

    Researchers at Karolinska Institutet and the Astrid Lindgren Children’s Hospital in Sweden have determined how children’s immune systems react to different kinds of cancer depending on their age. The study, which is published in the journal Cell, reveals significant differences between the immune response of children and adults, and has the potential to lead to new tailored treatments for children with cancer.

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