Research News

25 July 2024

Large genetic study on severe COVID-19 - Bonn researchers confirm three other genes for increased risk in addition to the known TLR7 gene

Whether or not a person becomes seriously ill with COVID-19 depends, among other things, on genetic factors. With this in mind, researchers from the University Hospital Bonn UKB and the University of Bonn, in cooperation with other research teams from Germany, the Netherlands, Spain and Italy, investigated a particularly large group of affected individuals.

25 July 2024

Fighting leukaemia by targeting its stem cells

Acute myeloid leukaemia is one of the deadliest cancers. Leukaemic stem cells responsible for the disease are highly resistant to treatment. A team from the University of Geneva UNIGE, University Hospital of Geneva HUG, and Inserm has made a breakthrough by identifying some of the genetic and energetic characteristics of these stem cells, notably a specific iron utilisation process.

23 July 2024

These healthcare professionals may be secret weapon against hypertension, study finds

When it comes to helping patients with high blood pressure get their hypertension under control, a new Tulane University study finds that pharmacists and community health workers have the best success rates.

18 July 2024

Diabetes Drug Reduces Drug Resistance in Lung Cancer

A medication used to treat diabetic neuropathy may make chemotherapy treatments more effective for patients with lung cancer, according to new findings from the University of Missouri School of Medicine published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

18 July 2024

New gene therapy for muscular dystrophy offers hope

A new gene therapy treatment for Duchenne muscular dystrophy shows promise of not only arresting the decline of the muscles of those affected by this inherited genetic disease, but perhaps, in the future, repairing those muscles.

17 July 2024

Supplements slow disease progression during late stage of dry age-related macular degeneration

In a new analysis of data, researchers at the National Institutes of Health (NIH) have found that taking a daily supplement containing antioxidant vitamins and minerals slows progression of late-stage dry age-related macular degeneration (AMD), potentially helping people with late-stage disease preserve their central vision. Researchers reviewed the original retinal scans of participants in the Age-Related Eye Diseases Studies (AREDS and AREDS2) and found that

17 July 2024

Harnessing big data helps scientists hone in on new antimicrobials

Researchers have developed a strategy to identify new antimicrobial drugs with therapeutic promise from bacterial datasets, providing clues for discovering alternatives to traditional antibiotics.

12 July 2024

Distinct T-cell signatures observed at different stages of type 1 diabetes development

A study conducted at the University of Eastern Finland found distinct signatures in CD8-positive T cells in blood samples from children with newly diagnosed type 1 diabetes and in autoantibody-positive children who later developed type 1 diabetes. The study was published in the journal Diabetes.

12 July 2024

Phage-Derived Enzyme Targets E. faecalis Biofilms to Mitigate Acute Graft-Versus-Host Disease

Acute graft-versus-host disease (aGVHD) is a medical condition that occurs when donor immune cells attack the recipient's tissues after an allogeneic hematopoietic stem cell transplantation (allo-HCT). The pathogenesis of aGVHD is influenced by gut dysbiosis and Enterococcus domination. Researchers from Japan recently identified a bacteriophage-derived enzyme called endolysin capable of targeting biofilms formed by Enterococcus faecalis. Their findings offer hope for tailored interventions in allo-HCT.

12 July 2024

Sleep timer for immune cells discovered

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus-infected cells but are inactive. A team from the Technical University of Munich has discovered that cells in blood vessels in the liver start a sleep timer that switches off immune cells. Targeting this mechanism could be a starting point for immunotherapies.

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Large genetic study on severe COVID-19 - Bonn researchers confirm three other genes for increased risk in addition to the known TLR7 gene

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