Rajasthan

UV SPECTROPHOTOMETRIC DETERMINATION OF OLMESARTAN MEDOXOMIL IN PURE AND PHARMACEUTICAL FORMULATION

ABOUT AUTHORS
PANDIYA HARSHADA*, RATHORE KS
Department of Pharmaceutics, B.N. College of Pharmacy, BN University, Udaipur- 313001

ABSTRACT
Olmesartan medoxomil (OM) is a new angiotensin II receptor antagonist agent. Olmesartan medoxomil is a prodrug, which, after ingestion, liberates the only active metabolite, olmesartan. Simple and sensitive method has been developed for determination of olmesartan medoxomil in both pure and pharmaceutical formulation. This method obeys Beer’s law in the concentration range of 15-55 µg/ml, exhibiting maximum absorption at 258.10 nm. In this method no interference from the common pharmaceutical excipients was observed. The developed and validated method was applied for the determination of olmesartan medoxomil in pharmaceutical dosage forms.

Applications are invited for Junior Research Fellow at BITS Pilani | M.Pharm, M.S Pharm

The Birla Institute of Technology & Science, BITS Pilani is an all-India Institute for higher education. The primary motive of BITS is to "train young men and women able and eager to create and put into action such ideas, methods, techniques and information". The Institute is a dream come true of its founder late Mr G.D.Birla - an eminent industrialist, a participant in Indian freedom struggle and a close associate of the Father of Indian Nation late Mr. Mohandas Karamchand Gandhi (Mahatma Gandhi). What started in early 1900s as a small school, blossomed into a set of colleges for higher education, ranging from the Humanities to Engineering until 1964 when all these colleges amalgamated to culminate into a unique Indian University of International standing. This university was christened as the Birla Institute of Technology and Science, Pilani, known to many as BITS, Pilani.

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