Pharma Analysis

NMR spectroscopy

Q.5.(c) In NMR spectroscopy, explain shift correlation spectra- COSY and its application in simplifying complex HNMR spectra.

Ans.5. (c) COSY (Correlation SpectroscopY): COSY is a method of two-dimensional spectroscopy and also known as H-H correlation spectroscopy.  In a COSY experiment, the chemical shift range of the proton spectrum is plotted on both axes.