Tamil Nadu

Transdermal Drug Delivery System: An Overview

About Authors:Niroj Shrestha*, D. Nagasamy Venkatesh**, Jeevan Sharma
J. S. S. College of Pharmacy, Ooty, Tamilnadu, India
*Final Year B.Pharmacy Student.
**For correspondence:
Department of Pharmaceutics
J. S. S. College of Pharmacy,
(A constituent college of JSS University, Mysore)
Ooty – 643 001.
Tamil Nadu, India.

Reference ID: PHARMATUTOR-ART-1068

Abstract
Transdermal drug delivery system (TDDS) has emerged as a potential novel drug delivery system in the last 30 years to improve the therapeutic efficacy and safety, maintain steady state plasma level of drugs and overcome significant drawbacks of the conventional oral dosage forms and parenteral preparations. TDDS is ideally suited for diseases that demand chronic treatment with frequent dosing. This review deals with a brief insight on the formulation aspects, the physical and chemical enhancers being explored to enhance the transdermal delivery of drugs across the stratum corneum, the evaluation parameters (physicochemical, in vitro, in vivo studies) and therapeutic applications of TDDS.

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